The effect of probiotic fermented milk and inulin on the functions and microecology of the intestine

被引:24
|
作者
Sairanen, Ulla
Piirainen, Laura
Grasten, Soile
Tompuri, Tuomo
Matto, Jaana
Saarela, Maria
Korpela, Riitta [1 ]
机构
[1] Valio Ltd R&D, Helsinki, Finland
[2] Univ Helsinki, Cent Hosp, Dept Allergy, Helsinki, Finland
[3] Univ Kuopio, Dept Clin Nutr, FIN-70211 Kuopio, Finland
[4] Univ Kuopio, Dept Physiol, FIN-70211 Kuopio, Finland
[5] VTT Tech Res Ctr Finland, Espoo, Finland
[6] Fdn Nutr Res, Helsinki, Finland
[7] Univ Helsinki, Inst Biomed Pharmacol, Helsinki, Finland
关键词
gastrointestinal symptoms; prebiotics; probiotics;
D O I
10.1017/S0022029907002713
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
We investigated the effects of a probiotic fermented milk and inulin on gastrointestinal function and microecology. The study was double-blinded and comprised 66 healthy adults (22 male, 44 female), mean age 40 years (range, 22-60 years). After a 12-d baseline period the subjects were randomized to consume, for 3 weeks, 3 x 200 ml daily of either (1) a fermented milk with probiotics (Bifidobacterium longum 1313536, Bifidobacterium spp. 420 and Lactobacillus acidophilus 145), (2) a fermented milk with the same probiotics plus 4 g inulin, or (3) a control fermented milk. During the last 7 d of the baseline and the intervention periods, the subjects kept a record of their defaecation frequency and gastrointestinal symptoms, and collected all their faeces. intestinal transit time, stool weight and faecal enzyme activities were measured. Thirty-nine subjects were randomized to give faecal samples for analysis of pH and microbes, including lactobacilli, bifidobacteria, coliforms, Escherichia coli, Bacteroides and Clostridium perfringens. Consumption of fermented milk with probiotics or with probiotics and inulin increased the faecal number of lactobacilli (P=0.009, P=0.003) and bifidobacteria (P=0.046, P=0.038) compared with the baseline. Compared with the control fermented milk, both active products increased lactobacilli (P=0.005, ANCOVA). Subjects consuming fermented milk with probiotics and inulin suffered from gastrointestinal symptoms, especially flatulence, more than the others (P < 0.001). In conclusion, the probiotic fermented milk product had a positive effect by increasing the number of lactobacilli and bifidobacteria in the colon. Inulin did not alter this effect but it increased gastrointestinal symptoms.
引用
收藏
页码:367 / 373
页数:7
相关论文
共 50 条
  • [11] Effect of Milk Type on the Microbiological, Physicochemical and Sensory Characteristics of Probiotic Fermented Milk
    Dimitrellou, Dimitra
    Salamoura, Chrysoula
    Kontogianni, Artemis
    Katsipi, Despoina
    Kandylis, Panagiotis
    Zakynthinos, George
    Varzakas, Theodoros
    MICROORGANISMS, 2019, 7 (09)
  • [12] Effect of refrigerated storage time on the viability of probiotic bacteria in fermented probiotic milk drinks
    Moayednia, Nasrin
    Ehsani, Mohamad R.
    Emamdjomeh, Zahra
    Mazaheri, Amir F.
    INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY, 2009, 62 (02) : 204 - 208
  • [13] PROBIOTIC AND NUTRITIONAL FEATURES IN FERMENTED MILK
    GARBATI, M
    INDUSTRIE ALIMENTARI, 1991, 30 (298): : 992 - 997
  • [14] EFFECT OF INULIN CONTAINING FERMENTED MILK ADMINISTRATION ON HUMAN INTESTINAL BACTERIAL FLORA
    Shen, You-Cheng
    Ko, Hui-Chung
    Huang, Yun-Chien
    Chen, Su-Lin
    Wang, Chin-Kun
    ANNALS OF NUTRITION AND METABOLISM, 2009, 55 : 440 - 440
  • [15] Evaluation of the effect of supplementing fermented milk with quinoa flour on probiotic activity
    Casarotti, Sabrina N.
    Carneiro, Bruno M.
    Penna, Ana Lucia B.
    JOURNAL OF DAIRY SCIENCE, 2014, 97 (10) : 6027 - 6035
  • [16] THE PROBIOTIC QUALITY DETERMINATION OF FERMENTED MILK FOOD
    Shabani, L.
    Sulovari, J.
    JOURNAL OF ENVIRONMENTAL PROTECTION AND ECOLOGY, 2011, 12 (4A): : 2352 - 2359
  • [17] Effect of dynamic high pressure on milk fermentation kinetics and rheological properties of probiotic fermented milk
    de Oliveira, Miguel Meirelles
    Duarte Augusto, Pedro Esteves
    da Cruz, Adriano Gomes
    Cristianini, Marcelo
    INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES, 2014, 26 : 67 - 75
  • [18] Mechanisms involved in the immunostimulation by probiotic fermented milk
    Maldonado Galdeano, Carolina
    de Moreno de LeBlanc, Alejandra
    Carmuega, Esteban
    Weill, Ricardo
    Perdigon, Gabriela
    JOURNAL OF DAIRY RESEARCH, 2009, 76 (04) : 446 - 454
  • [19] Effect of inulin on the microflora of an ABT-type fermented milk during refrigerated storage
    Varga, L.
    Gyenis, B.
    Molnar, N.
    Szigeti, J.
    JOURNAL OF ANIMAL SCIENCE, 2004, 82 : 164 - 164
  • [20] Effect of inulin on the microflora of an ABT-type fermented milk during refrigerated storage
    Varga, L.
    Gyenis, B.
    Molnar, N.
    Szigeti, J.
    JOURNAL OF DAIRY SCIENCE, 2004, 87 : 164 - 164