Engineering Kapβ2 to recover nuclear localization of ALS-associated mutant FUS.

被引:0
|
作者
Fare, C. M. [1 ]
Guo, L. [1 ]
Shorter, J. [1 ]
机构
[1] Univ Penn, Dept Biochem & Biophys, Philadelphia, PA 19104 USA
关键词
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
P3333
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations
    Sébastien Feuillette
    Morgane Delarue
    Gaëtan Riou
    Anne-Lise Gaffuri
    Jane Wu
    Zsolt Lenkei
    Olivier Boyer
    Thierry Frébourg
    Dominique Campion
    Magalie Lecourtois
    Journal of Molecular Neuroscience, 2017, 62 : 114 - 122
  • [22] Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations
    Feuillette, Sebastien
    Delarue, Morgane
    Riou, Gaetan
    Gaffuri, Anne-Lise
    Wu, Jane
    Lenkei, Zsolt
    Boyer, Olivier
    Frebourg, Thierry
    Campion, Dominique
    Lecourtois, Magalie
    JOURNAL OF MOLECULAR NEUROSCIENCE, 2017, 62 (01) : 114 - 122
  • [23] Xrp1 genetically interacts with the ALS-associated FUS orthologue caz and mediates its toxicity
    Mallik, Moushami
    Catinozzi, Marica
    Hug, Clemens B.
    Zhang, Li
    Wagner, Marina
    Bussmann, Julia
    Bittern, Jonas
    Mersmann, Sina
    Klambt, Christian
    Drexler, Hannes C. A.
    Huynen, Martijn A.
    Vaquerizas, Juan M.
    Storkebaum, Erik
    JOURNAL OF CELL BIOLOGY, 2018, 217 (11): : 3947 - 3964
  • [24] Nuclear localization of SMN and FUS is not altered in fibroblasts from patients with sporadic ALS
    Kariya, Shingo
    Sampson, Jacinda B.
    Northrop, Lesley E.
    Lucarelli, Christopher M.
    Naini, Ali B.
    Re, Diane B.
    Hirano, Michio
    Mitsumoto, Hiroshi
    AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2014, 15 (7-8) : 581 - 587
  • [25] The ALS-associated proteins FUS and TDP-43 induce neurotoxicity but act via divergent pathways in Drosophila
    Pan, X.
    Schulz, J. B.
    Voigt, A.
    JOURNAL OF NEUROCHEMISTRY, 2013, 125 : 251 - 251
  • [26] ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects
    Qiu, Haiyan
    Lee, Sebum
    Shang, Yulei
    Wang, Wen-Yuan
    Au, Kin Fai
    Kamiya, Sherry
    Barmada, Sami J.
    Finkbeiner, Steven
    Lui, Hansen
    Carlton, Caitlin E.
    Tang, Amy A.
    Oldham, Michael C.
    Wang, Hejia
    Shorter, James
    Filiano, Anthony J.
    Roberson, Erik D.
    Tourtellotte, Warren G.
    Chen, Bin
    Tsai, Li-Huei
    Huang, Eric J.
    JOURNAL OF CLINICAL INVESTIGATION, 2014, 124 (03): : 981 - 999
  • [27] Hu Antigen R Is a Positive Regulator of ALS-Associated RNA Binding Proteins TDP-43 and FUS
    Lu, Liang
    Zheng, Lei
    Si, Ying
    King, Peter
    NEUROLOGY, 2016, 86
  • [28] Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations
    Finelli, Mattea J.
    Liu, Kevin X.
    Wu, Yixing
    Oliver, Peter L.
    Davies, Kay E.
    HUMAN MOLECULAR GENETICS, 2015, 24 (12) : 3529 - 3544
  • [29] The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span
    Wang, Ji-Wu
    Brent, Jonathan R.
    Tomlinson, Andrew
    Shneider, Neil A.
    McCabe, Brian D.
    JOURNAL OF CLINICAL INVESTIGATION, 2011, 121 (10): : 4118 - 4126
  • [30] High Resolution Structural Analysis Of ALS-Associated Mutant SOD1 Inclusion Bodies
    Naser, Dalia
    Tarasca, Michael
    Mishra, Gyana
    Soule, Tyler
    Deol, Harmeen
    Meiering, Elizabeth
    FASEB JOURNAL, 2021, 35