Oxygen radical production of emigrated, intra-abdominal PMNL in patients with secondary peritonitis

被引：0
|
作者：
Holzer, K [1 ]
Richter, A [1 ]
Henrich, D [1 ]
Encke, A [1 ]
机构：
[1] Univ Frankfurt Klinikum, Klin Allgemein & Gefasschirurg, D-60590 Frankfurt, Germany
来源：
LANGENBECKS ARCHIVES OF SURGERY | 1999年
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D O I：
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中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Oxygen radical production of emigrated, intra-abdominal and circulating polymorphonuclear leukocytes (ePMNL, cPMNL) were investigated in patients with secondary peritonitis. Spontaneous oxygen radical production of ePMNL and cPMNL was high in patients with peritonitis. Despite absent relaparotomy oxygen radical production of ePMNL and cPMNL increased 24h after operation in the group with peritonitis. There was no further activation of spontaneous oxygen radical production of ePMNL with TNF-alpha in vitro. Surgical trauma alone was able to enhance PMNL emigration in the abdomen but spontaneous oxygen radical production of ePMN and cPMNL was low. In the control group TNF-alpha was able to increase spontaneous oxygen radical production of ePMNL significantly.
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页码：511 / 514
页数：4
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