Impact of brachytherapy applicators geometry on dose distribution in gynaecological cancer

被引:0
|
作者
Rehman, Ateeque Ur [1 ]
Buzdar, Saeed Ahmad [1 ]
Hassan, Muhammad [1 ]
Gadi, Asghar [2 ]
Khan, Muhammad Afzal [1 ]
Anjum, Muhammad Naeem [1 ]
机构
[1] Islamia Univ Bahawalpur, Dept Phys, Bahawalpur, Pakistan
[2] Bahawalpur Inst Nucl Med & Oncol, Bahawalpur, Pakistan
关键词
Intracavitary Brachytherapy; Applicator Geometry; Dose; Gynaecological Cancer; CARCINOMA; DOSIMETRY;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To evaluate the efficacy of suitable applicators for intracavitary brachytherapy to treat cervical cancer. Methods: This study was conducted at the Bahawalpur Institute of Nuclear Medicine and Oncology, Bahawalpur, Pakistan, in February 2014. Dose distributions for Fletcher and ring applicators were analysed at target points according to recommended protocols using Abacus software. The doses to the organs at risk, i.e. bladder and rectum, were also focused. SPSS 16 was used for data analysis. Results: A total of 40 patients' plans were considered. The mean absorbed dose at target point A was 6.87 +/- 0.201Gy in case of Fletcher applicator (p = 0.082) and 6.79 +/- 0.107Gy in case of ring applicator (p = 0.001). Absorbed dose at the target point was significantly higher for the Fletcher type applicators as compared to the ring applicators. However, the amount of doses at bladder and rectum were smaller for the Fletcher applicators. Conclusion: Fletcher applicator was more effective in achieving a better dose distribution in gynaecological malignancies, resulting in better treatment outcome.
引用
收藏
页码:1566 / 1570
页数:5
相关论文
共 50 条
  • [1] Patient-related factors determining geometry of intracavitary applicators and pelvic dose distribution during cervical cancer brachytherapy
    SenkusKonefka, E
    Kobierska, A
    Jassem, J
    Badzio, A
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1997, 37 (03): : 531 - 536
  • [2] MARKERS TO BE USED WITH MR COMPATIBLE GYNAECOLOGICAL BRACHYTHERAPY APPLICATORS
    Bengtsson, E.
    Vargas, R.
    Nordell, B.
    Lundell, M.
    RADIOTHERAPY AND ONCOLOGY, 2008, 88 : S427 - S427
  • [3] The impact of number of the Norman Simon (NS) applicators on dose distribution in endometrial cancer patients treated with pulsed dose rate brachytherapy (PDR BT)
    Tarnawska, Z
    Serkies, K
    Jassem, J
    RADIOTHERAPY AND ONCOLOGY, 2004, 71 : S86 - S87
  • [4] Improving dose delivery by adding interstitial catheters to fixed geometry applicators in high-dose-rate brachytherapy for cervical cancer
    Otter, Sophie
    Coates, Amanda
    Franklin, Adrian
    Cunningham, Melanie
    Stewart, Alexandra
    BRACHYTHERAPY, 2018, 17 (03) : 580 - 586
  • [5] CT based dose distribution and optimization for gynaecological pulsed dose rate interstitial brachytherapy
    Brunaud, C
    Ahmad, F
    Peiffert, D
    Metayer, Y
    Aletti, P
    RADIOTHERAPY AND ONCOLOGY, 2004, 71 : S78 - S78
  • [6] A novel approach to locating source dwell positions in HDR brachytherapy gynaecological applicators
    Franich, R.
    Hanlon, M.
    Smith, R. L.
    Demsey, C.
    Millar, J. L.
    RADIOTHERAPY AND ONCOLOGY, 2016, 119 : S473 - S474
  • [7] Comparison of Dose Distribution in Different Types of Cylindrical Applicators Using High Dose Rate Cobalt-60 Source Brachytherapy in Gynecological Cancer
    Abtahi, M.
    Gholami, S.
    Maddah-Safaei, A.
    MEDICAL PHYSICS, 2021, 48 (06)
  • [8] Accurate Surface Dose Determination for Electronic Brachytherapy Applicators
    Segala, J.
    Cardarelli, G.
    Hiatt, J.
    Curran, B.
    Sternick, E.
    MEDICAL PHYSICS, 2009, 36 (06)
  • [9] Inverse Planning the Geometry of Intracavitary Applicators Used in GYN Brachytherapy
    Platt, M.
    Lamba, M.
    Kassing, W.
    Ionascu, D.
    MEDICAL PHYSICS, 2018, 45 (06) : E240 - E240
  • [10] Automated Dose Point Placement for Cervical Cancer Brachytherapy Using Tandem and Ovoid Applicators
    Kang, H.
    Padilla, L.
    Hasan, Y.
    Al-Hallaq, H.
    MEDICAL PHYSICS, 2015, 42 (06) : 3364 - 3364