Solid-phase combinatorial synthesis of polyamine derivatives using aminoalcohol building blocks

被引：23

作者：

Renault, J ^{[1
]}

Lebranchu, M ^{[1
]}

Lecat, A ^{[1
]}

Uriac, P ^{[1
]}

机构：

[1] Univ Rennes 1, Fac Sci Biol & Med, UPRES Synth & Extract Mol Visee Therapeut 2234, F-35043 Rennes, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 38期

关键词：

polyamines; combinatorial synthesis; solid-phase synthesis;

D O I：

10.1016/S0040-4039(01)01352-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A systematic study of nucleophilic displacement of mesyl groups using benzylamine was carried out on Multipin Synphase(TM) supports. The optimal conditions were applied for the combinatorial synthesis of polyamine derivatives from commercially available aminoalcohols and amines. (C) 2001 Published by Elsevier Science Ltd.

引用

页码：6655 / 6658

页数：4

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