A simple clinical method to identify women at higher risk of preeclampsia

被引：2
|
作者：
Viguiliouk, Effie [1 ]
Park, Alison L. [2 ]
Berger, Howard [3 ]
Geary, Michael P. [3 ]
Ray, Joel G. [3 ,4 ,5 ]
机构：
[1] Univ Toronto, Toronto, ON, Canada
[2] Inst Clin Evaluat Sci, Toronto, ON, Canada
[3] Univ Toronto, St Michaels Hosp, Dept Obstet & Gynecol, Toronto, ON, Canada
[4] Univ Toronto, St Michaels Hosp, Dept Med, Toronto, ON, Canada
[5] Univ Toronto, St Michaels Hosp, Dept Hlth Policy Management & Evaluat, Toronto, ON, Canada
来源：
PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH | 2017年 / 10卷
关键词：
Preeclampsia; Preterm birth; Pregnancy; Prediction; C-statistic; Hypertension; PRETERM;
D O I：
10.1016/j.preghy.2017.07.145
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
An outstanding issue is how to efficiently identify women at high risk of preeclampsia. This retrospective cohort study included 8672 pregnancies at a single centre in Toronto. We tested our simple method presence vs. absence of >1 major (pre-pregnancy BMI > 30 kg/m(2), chronic hypertension, pre-pregnancy diabetes mellitus and assisted reproductive therapy) or >= 2 minor (prior stillbirth, age >40 years, nulliparity, multifetal pregnancy, chronic kidney disease, and SLE) risk factors for PE. The RR of PE was 8.4 (95% CI 5.3-13.2) and the model C-statistic 0.74 (95% CI 0.69-0.79). Further testing of this method elsewhere is warranted. (C) 2017 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：10 / 13
页数：4
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