Streptomycin-dependent exhibition of cytokine-inducing activity in streptomycin-dependent Mycobacterium tuberculosis strain 18b

被引：4
|
作者：
Fukasawa, Y
Kawamura, I
Uchiyama, R
Yamamoto, K
Kaku, T
Tominaga, T
Nomura, T
Ichiyama, S
Ezaki, T
Mitsuyama, M
机构：
[1] Kyoto Univ, Grad Sch Med, Dept Microbiol, Sakyo Ku, Kyoto 6068501, Japan
[2] Kyoto Univ, Grad Sch Med, Dept Clin Lab Med, Kyoto 6068501, Japan
[3] Gifu Univ, Grad Sch Med, Dept Microbiol Regenerat & Adv Med Sci, Gifu, Japan
来源：
INFECTION AND IMMUNITY | 2005年 / 73卷 / 10期
关键词：
D O I：
10.1128/IAI.73.10.7051-7055.2005
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Peritoneal exudate cells of mice were stimulated with a streptomycin-dependent Mycobacterium tuberculosis strain, 18b. Gamma interferon production by natural killer cells depending on interleukin-12 and interleukin-18 was induced only in the presence of a high dose of streptomycin. This study suggested the requirement of active bacterial metabolism for this host response.
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页码：7051 / 7055
页数：5
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