Highly selective ratiometric fluorescent probes for the detection of Fe3+ and its application in living cells

被引:19
|
作者
Li, Chunqing [1 ]
Sun, Qi [1 ]
Zhao, Qiang [2 ]
Cheng, Xinjian [1 ]
机构
[1] Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430073, Peoples R China
[2] Nankai Univ, Coll Life Sci, Tianjin 300071, Peoples R China
基金
中国国家自然科学基金;
关键词
Ratiometric probe; Colorimetric probe; NIR; Bioimaging; TURN-ON SENSOR; BODIPY; COUMARIN; SPECTRA; COMPLEX; BOWEL; IONS; FRET; DYES; HG2+;
D O I
10.1016/j.saa.2019.117720
中图分类号
O433 [光谱学];
学科分类号
0703 ; 070302 ;
摘要
It's of vital importance to detect heavy metals in environment and living cells. In this work, four near-infrared regions boron dipyrromethene (BODIPY) probes (QBPH, PBPH, QBP and PBP) are constructed based on two BODIPY precursors (QB, PB) for sensing of Fe3+. As expected, these four probes exhibit obvious colorimetric and ratiometric response to Fe3+. In addition, QBP and PBP display highly sensitive and selective performance for detection of Fe3+. More importantly, QBP and PBP are successfully applied to near infrared imaging and detection of Fe3+ in living A549 cells; it indicates that these novel designed probes could be a useful tool for the studies of Fe3+ in living cells. (C) 2019 Elsevier B.V. All rights reserved.
引用
收藏
页数:10
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