VIRTUAL SCREENING AND IN VITRO ASSAYS OF LIGANDS WITH ACTIVITY AGAINST DIPEPTIDYL PEPTIDASE-4 (DPP-4) ENZYME

被引:0
|
作者
Pantaleao, Simone Queiroz [1 ]
Philot, Eric Allison [2 ]
De Paula, Heberth [3 ]
De Sairre, Mirela Ines [1 ]
Lima, Angelica Nakagawa [4 ]
Dos Santos, Raquel Alves [5 ]
Scott, Ana Ligia [2 ]
Honorio, Kathia Maria [1 ]
机构
[1] Fed Univ ABC, Ctr Sci Nat & Human, Sao Paulo, Brazil
[2] Fed Univ ABC, Ctr Math Comp & Cognit, Sao Paulo, Brazil
[3] Univ Fed Espirito Santo, Ctr Exact Nat & Hlth Sci, Espirito Santo, Brazil
[4] Fed Univ ABC, Ctr Engn Modeling & Appl Social Sci, Sao Paulo, Brazil
[5] Univ Franca, Lab Genet & Mol Biol, Sao Paulo, Brazil
关键词
Diabetes; DPP-4; Drug discovery;
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
CD.21
引用
收藏
页码:1332 / 1332
页数:1
相关论文
共 50 条
  • [41] Dipeptidyl peptidase-4 (DPP4) inhibition in COVID-19
    Solerte, Sebastiano Bruno
    Di Sabatino, Antonio
    Galli, Massimo
    Fiorina, Paolo
    ACTA DIABETOLOGICA, 2020, 57 (07) : 779 - 783
  • [42] Dipeptidyl peptidase-4 (DPP4) inhibition in COVID-19
    Sebastiano Bruno Solerte
    Antonio Di Sabatino
    Massimo Galli
    Paolo Fiorina
    Acta Diabetologica, 2020, 57 : 779 - 783
  • [43] DIPEPTIDYL PEPTIDASE 4 (DPP-4): AN EMERGING BIOMARKER OF DISEASE ACTIVITY AND PROGNOSIS IN INFLAMMATORY BOWEL DISEASES
    Pinto-Lopes, Pedro
    Afonso, Joana
    Macedo, Guilherme
    Magro, Fernando
    GASTROENTEROLOGY, 2017, 152 (05) : S770 - S770
  • [44] α-Amylase and dipeptidyl peptidase-4 (DPP-4) inhibitory effects of Melicope latifolia bark extracts and identification of bioactive constituents using in vitro and in silico approaches
    Quek, Alexandra
    Kassim, Nur Kartinee
    Lim, Pei Cee
    Tan, Dai Chuan
    Mohammad Latif, Muhammad Alif
    Ismail, Amin
    Shaari, Khozirah
    Awang, Khalijah
    PHARMACEUTICAL BIOLOGY, 2021, 59 (01) : 964 - 973
  • [45] Reduced humidity induces skin barrier dysfunction and secretion of dipeptidyl peptidase-4 (DPP-4) in a skin-equivalent model
    Lee, Sung Hoon
    Bae, Il-Hong
    Marinho, Paulo A.
    Lee, Chang Seok
    Lee, Jongsung
    ARCHIVES OF BIOLOGICAL SCIENCES, 2019, 71 (04) : 697 - 702
  • [46] Protective Effects of Dipeptidyl Peptidase-4 (DPP-4) Inhibitor against Increased β Cell Apoptosis Induced by Dietary Sucrose and Linoleic Acid in Mice with Diabetes
    Shirakawa, Jun
    Amo, Kikuko
    Ohminami, Hirokazu
    Orime, Kazuki
    Togashi, Yu
    Ito, Yuzuru
    Tajima, Kazuki
    Koganei, Megumi
    Sasaki, Hajime
    Takeda, Eiji
    Terauchi, Yasuo
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (29) : 25467 - 25476
  • [47] Comparative pharmacology of the Dipeptidyl Peptidase-4 (DPP-4) metabolites of GLP-1 and the GLP-1 analogue, liraglutide
    Tomaselli, K.
    Herich, J.
    Xu, K.
    Yuskin, D.
    Collins, L.
    Crogan-Grundy, C.
    Wang, Y.
    Brunel, F.
    Lopez, J. Alfaro
    Sharma, A.
    Hanley, M.
    Ghosh, S.
    DIABETOLOGIA, 2009, 52 : S305 - S305
  • [48] The impact of sitagliptin, inhibitor of dipeptidyl peptidase-4 (DPP-4), on the ADMA-DDAH-NO pathway in ischemic and reperfused rat livers
    Trocha, Malgorzata
    Nowak, Beata
    Merwid-Lad, Anna
    Szuba, Andrzej
    Dziegiel, Piotr
    Pisniewska, Malgorzata
    Gomulkiewicz, Agnieszka
    Wisniewski, Jerzy
    Piasecki, Tomasz
    Gziut, Magdalena
    Szelag, Adam
    Sozanski, Tomasz
    ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, 2018, 27 (11): : 1483 - 1490
  • [49] Association of serum and salivary dipeptidyl peptidase-4 (DPP-4) with oral cancerous and precancerous lesions; an observational diagnostic accuracy study
    Abdel Fattah Tarrad, Nayroz
    Gamil Shaker, Olfat
    Abdelkawy, Maha
    Hassan, Sandy
    BMC ORAL HEALTH, 2024, 24 (01):
  • [50] The dipeptidyl peptidase-4 (DPP-4) inhibitor vildagliptin improves insulin sensitivity and β-cell function in subjects with impaired fasting glucose
    Jacobsen, Lisbeth V.
    Hindsberger, Charlotte
    Robson, Richard
    Zdravkovic, Milan
    DIABETES, 2007, 56 : A137 - A137