A simple effective method for estimating the [18O] enrichment of water mixtures

被引：3
|
作者：
Fawdry, RM [1 ]
机构：
[1] Royal Prince Alfred Hosp, PET & Nucl Med, Camperdown, NSW 2050, Australia
来源：
APPLIED RADIATION AND ISOTOPES | 2004年 / 60卷 / 01期
关键词：
PET; O-18; enriched water;
D O I：
10.1016/j.apradiso.2003.09.010
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Isotopically enriched water, [O-18] H2O, recovered from the synthesis of [F-18] fluorine-labelled PET radio-pharmaceuticals, is frequently diluted with natural water, [O-16] H2O. The extent of isotope dilution limits the usefulness of the recovered water. A simple method for determining the [O-18] enrichment of water mixtures could aid PET cyclotron facilities to calculate the [F-18] yields to be expected when the recovered [O-18] H2O is reused. A gravimetric method (repeatability for high enrichment +/-0.3% [O-18], detection limit similar to2% [O-18] enrichment) is described. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：23 / 26
页数：4
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