Activation of either PAR1 or PAR4 on human platelets can elicit expression of maximum platelet procoagulant activity.

被引：0
|
作者：
Heger, CD [1 ]
Mosley, CN [1 ]
Tracy, PB [1 ]
机构：
[1] Univ Vermont, Coll Med, Burlington, VT USA
来源：
BLOOD | 2001年 / 98卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
2163
引用
收藏
页码：518A / 518A
页数：1
相关论文
共 50 条
  • [1] PAR1, but not PAR4, regulates human platelet activation through PLD
    Holinstat, M
    Voss, B
    Bilodeau, ML
    Hamm, HE
    FASEB JOURNAL, 2006, 20 (04): : A695 - A696
  • [2] Effect of PAR1 and PAR4 agonists on platelet activity
    Buryachkovskaya, L., I
    Strukova, S. M.
    Uchitel, I. A.
    Sumarokov, A. B.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2011, 9 : 781 - 781
  • [3] Direct thrombin inhibitor bivalirudin attenuates activation of human platelets through PAR1 and PAR4
    Holinstat, Michael
    Hudson, W. J.
    Hamm, Heidi E.
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2008, 28 (06) : E71 - E71
  • [4] Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets
    Covic, L
    Gresser, AL
    Kuliopulos, A
    BIOCHEMISTRY, 2000, 39 (18) : 5458 - 5467
  • [5] Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets.
    Covic, L
    Gresser, AL
    Kuliopulos, A
    FASEB JOURNAL, 2000, 14 (08): : A1347 - A1347
  • [6] Platelet thrombin receptors PAR1 and PAR4 act in a synergistic manner
    Oberg, K., V
    Kulsum, S.
    Boknas, N.
    Ramstrom, S.
    Lindahl, T. L.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 : 629 - 629
  • [7] Comparison of the effects of PAR1 antagonists, PAR4 antagonists, and their combinations on thrombin-induced human platelet activation
    Wu, Chin-Chung
    Teng, Che-Ming
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2006, 546 (1-3) : 142 - 147
  • [8] Contributions of Protease-Activated Receptors PAR1 and PAR4 to Thrombin-Induced GPIIbIIIa Activation in Human Platelets
    Duvernay, Matthew T.
    Temple, Kayla J.
    Maeng, Jae G.
    Blobaum, Anna L.
    Stauffer, Shaun R.
    Lindsley, Craig W.
    Hamm, Heidi E.
    MOLECULAR PHARMACOLOGY, 2017, 91 (01) : 39 - 47
  • [9] Platelet response to activation of thrombin receptors, PAR1 and PAR4, is impaired in human platelets deficient in Gαq or phospholipase C-β2.
    Vaidyula, VR
    Rao, AK
    BLOOD, 2001, 98 (11) : 25A - 26A
  • [10] Modulation of platelet reactivity to thrombin by flavonoids: interference on PAR1 and PAR4 signaling
    Navarro-Nunez, L.
    Lozano, M.
    Guerrero, J.
    Martinez, C.
    Vicente, V.
    Castillo, J.
    Rivera, J.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 : 635 - 635
12345