Chemistry and Biological Activity of Essential Oils from Piper claussenianum (Piperaceae)

被引：0
|
作者：
Marques, Andre M. [1 ]
Barreto, Anna Lea S. [2 ]
Batista, Eber M. [2 ]
Curvelo, Jose Alexandre da R. [2 ]
Velozo, Leosvaldo S. M. [1 ]
Moreira, Davyson de L. [3 ]
Guimaraes, Elsie F. [4 ]
Soares, Rosangela Maria A. [2 ]
Kaplan, Maria Auxiliadora C. [1 ]
机构：
[1] Univ Fed Rio de Janeiro, NPPN, Ctr Ciencias Saude, BR-21941590 Rio De Janeiro, Brazil
[2] Univ Fed Rio de Janeiro, Dept Microbiol Geral, Inst Microbiol Prof Paulo de Goes, BR-21941590 Rio De Janeiro, Brazil
[3] Fiocruz MS, Dept Nat Prod, BR-21041250 Rio De Janeiro, Brazil
[4] Inst Pesquisa Jardim Bot Rio de Janeiro, BR-22460030 Rio De Janeiro, Brazil
来源：
NATURAL PRODUCT COMMUNICATIONS | 2010年 / 5卷 / 11期
关键词：
Piperaceae; Piper claussenianum; (E)-nerolidol; linalool; essential oil; Leishmania amazonensis; ANTILEISHMANIAL ACTIVITY; ADUNCUM;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Analyses of essential oils obtained from fresh and dried leaves and inflorescences of Piper clausenianum were performed using GC-FID, GC-MS and NMR techniques Forty compounds were detected for these four oils with the total of identified constituents ranging from 88 7% for the dried inflorescences to 97 7% for the dried leaves Sesquiterpenes were the main constituents in the volatile fraction from leaves with a high percentage of (E)-nerolidol (up to 83%) However, monoterpenes were identified in greater amount in the inflorescences, with linalool percentages from 50% up The essential oils from fresh leaves and inflorescences were submitted to anti-parasitic activity against a strain of Leishmania amazonensis Both samples showed biological activity, but the essential oil from P claussenianum fresh leaves, which was rich in (E)-nerolidol showed effective growth inhibition of L amazonensis due to the high percentage of this metabolite in the mixture
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页码：1837 / 1840
页数：4
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