Invasive mucormycosis during treatment for acute lymphoblastic leukaemia-successful management of two life-threatening diseases

被引：4

作者：

Trobisch, Andreas ^{[1
,2
]}

Marterer, R. ^{[3
]}

Gorkiewicz, G. ^{[4
]}

Flaschberger, S. ^{[5
]}

Lackner, H. ^{[1
]}

Seidel, M. ^{[1
]}

Sperl, D. ^{[1
]}

Karastaneva, A. ^{[1
]}

Kohlmaier, B. ^{[1
]}

Egger, M. ^{[6
]}

Urban, C. ^{[1
]}

Benesch, M. ^{[1
]}

Strenger, V ^{[1
,6
,7
]}

机构：

[1] Med Univ, Dept Paediat & Adolescent Med, Div Paediat Haematol Oncol, Graz, Austria

[2] Med Univ, Dept Paediat & Adolescent Med, Div Neonatol, Graz, Austria

[3] Med Univ Graz, Dept Radiol, Div Paediat Radiol, Graz, Austria

[4] Med Univ, Diagnost & Res Inst Pathol, Graz, Austria

[5] Klinikum Klagenfurt Worthersee, Dept Paediat, Klagenfurt, Austria

[6] Med Univ, Dept Paediat & Adolescent Med, Div Paediat Pulmonol & Allergol, Graz, Austria

[7] Med Univ, Res Unit Infect Dis Immunocompromised Host, Graz, Austria

来源：

SUPPORTIVE CARE IN CANCER | 2020年 / 28卷 / 05期

关键词：

ALL; Mucormycosis; IFD; Antimycotic treatment; Chemotherapy; LIPOSOMAL AMPHOTERICIN-B; ACTINOMUCOR-ELEGANS; EUROPEAN ORGANIZATION; FUNGAL-INFECTIONS; DIAGNOSIS; GUIDELINES;

D O I：

10.1007/s00520-019-04962-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 5-year-old patient treated for acute lymphoblastic leukaemia (ALL) developed proven pulmonary invasive fungal disease (IFD) due to Actinomucor elegans. While completing ALL treatment according to AIEOP ALL protocol 2009 for further 15 months, antifungal treatment with liposomal amphotericin B and intermittent additional posaconazole was continued until immune reconstitution 7 months after the end of ALL treatment. Repeated imaging guided treatment decisions. Twenty-six and 19 months after the end of ALL treatment and antifungal treatment, respectively, the patient is still in the first complete remission and shows no signs of active invasive fungal disease (IFD).

引用

页码：2157 / 2161

页数：5

共 47 条

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