Determination of lidocaine in dental pulp by high-performance liquid chromatography

被引：9
|
作者：
Kanjanawattana, S
Mangkornkarn, C
Wilairat, P
Vongsavan, N
机构：
[1] Mahidol Univ, Dept Operat Dent, Master Program Endodont, Fac Dent, Bangkok 10700, Thailand
[2] Mahidol Univ, Fac Dent, Dept Physiol & Biochem, Bangkok 10700, Thailand
[3] Mahidol Univ, Fac Sci, Dept Chem, Bangkok 10700, Thailand
来源：
JOURNAL OF ENDODONTICS | 2001年 / 27卷 / 01期
关键词：
D O I：
10.1097/00004770-200101000-00009
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
The purpose of this study was to develop a method for lidocaine detection in dental pulp by high-performance liquid chromatography. The amounts of lidocaine in dog pulps were quantitated after local injection to evaluate lidocaine recovery from pulp tissue with this technique. Comparison was also made between the amount of lidocaine found in upper and lower canines, The high-performance liquid chromatography system was shown to be a reliable and reproducible tool for lidocaine determination. Lidocaine extraction from the tissue showed recovery of 90%. The amount of lidocaine recovered from the upper canine (0.21 mug/mg) was higher than the lower canine (0.17 mug/mg).
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页码：31 / 35
页数：5
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