SARS-CoV-2 seroprevalence among the general population and healthcare workers in India, December 2020-January 2021

被引：82

作者：

Murhekar, Manoj, V ^{[1
]}

Bhatnagar, Tarun ^{[1
]}

Thangaraj, Jeromie Wesley Vivian ^{[1
]}

Saravanakumar, V ^{[1
]}

Kumar, Muthusamy Santhosh ^{[1
]}

Selvaraju, Sriram ^{[2
]}

Rade, Kiran ^{[3
]}

Kumar, C. P. Girish ^{[1
]}

Sabarinathan, R. ^{[1
]}

Turuk, Alka ^{[4
]}

Asthana, Smita ^{[5
]}

Balachandar, Rakesh ^{[6
]}

Bangar, Sampada Dipak ^{[7
]}

Bansal, Avi Kumar ^{[8
]}

Chopra, Vishal ^{[9
]}

Das, Dasarathi ^{[10
]}

Deb, Alok Kumar ^{[11
]}

Devi, Kangjam Rekha ^{[12
]}

Dhikav, Vikas ^{[13
]}

Dwivedi, Gaurav Raj ^{[14
]}

Khan, S. Muhammad Salim ^{[15
]}

Kumar, M. Sunil ^{[16
]}

Laxmaiah, Avula ^{[17
]}

Madhukar, Major ^{[18
]}

Mahapatra, Amarendra ^{[10
]}

Rangaraju, Chethana ^{[19
]}

Turuk, Jyotirmayee ^{[10
]}

Yadav, Rajiv ^{[20
]}

Andhalkar, Rushikesh ^{[2
]}

Arunraj, K. ^{[2
]}

Bharadwaj, Dinesh Kumar ^{[17
]}

Bharti, Pravin ^{[20
]}

Bhattacharya, Debdutta ^{[10
]}

Bhat, Jyothi ^{[20
]}

Chahal, Ashrafjit S. ^{[9
]}

Chakraborty, Debjit ^{[11
]}

Chaudhury, Anshuman ^{[2
]}

Deval, Hirawati ^{[14
]}

Dhatrak, Sarang ^{[6
]}

Dayal, Rakesh ^{[21
]}

Elantamilan, D. ^{[13
]}

Giridharan, Prathiksha ^{[2
]}

Haq, Inaamul ^{[15
]}

Hudda, Ramesh Kumar ^{[13
]}

Jagjeevan, Babu ^{[17
]}

Kalliath, Arshad ^{[16
]}

Kanungo, Srikanta ^{[10
]}

Krishnan, Nivethitha N. ^{[2
]}

Kshatri, Jaya Singh ^{[10
]}

Kumar, Alok ^{[2
]}

机构：

[1] ICMR Natl Inst Epidemiol, Chennai 600077, Tamil Nadu, India

[2] ICMR Natl Inst Res TB, Chennai, Tamil Nadu, India

[3] Who Country Off India, New Delhi, India

[4] Indian Council Med Res, New Delhi, India

[5] ICMR Natl Inst Canc Prevent & Res, Noida, Uttar Pradesh, India

[6] ICMR Natl Inst Occupat Hlth, Ahmadabad, Gujarat, India

[7] ICMR Natl AIDS Res Inst, Pune, Maharashtra, India

[8] ICMR Natl JALMA Inst Leprosy & Other Mycobacteria, Agra, Uttar Pradesh, India

[9] State TB Training & Demonstrat Ctr, Patiala, Punjab, India

[10] ICMR Reg Med Res Ctr, Bhubaneswar, Odisha, India

[11] ICMR Natl Inst Cholera & Enter Dis, Kolkata, W Bengal, India

[12] ICMR Reg Med Res Ctr, Dibrugarh, Assam, India

[13] ICMR Natl Inst Implementat Res Noncommunicable Di, Jodhpur, Rajasthan, India

[14] ICMR Reg Med Res Ctr, Gorakhpur, Uttar Pradesh, India

[15] Govt Med Coll Srinagar, Jammu, Jammu & Kashmir, India

[16] State TB Training & Demonstrat Ctr, Thiruvananthapuram, Kerala, India

[17] ICMR Natl Inst Nutr, Hyderabad, Telangana, India

[18] ICMR Rajendra Mem Res Inst Med Sci, Patna, Bihar, India

[19] Bangalore & Lady Willingdon State TB Ctr, Natl TB Inst, Bengaluru, Karnataka, India

[20] ICMR Natl Inst Res Tribal Hlth, Jabalpur, Madhya Pradesh, India

[21] State TB Training & Demonstrat Ctr, Ranchi, Bihar, India

[22] State TB Off, Hyderabad, Andhra Pradesh, India

[23] State TB Training & Demonstrat Ctr, Raipur, Madhya Pradesh, India

来源：

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2021年 / 108卷

关键词：

SARS-CoV-2; COVID-19; IgG; Seroprevalence; India;

D O I：

10.1016/j.ijid.2021.05.040

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Background: Earlier serosurveys in India revealed seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) of 0.73% in May-June 2020 and 7.1% in August-September 2020. A third serosurvey was conducted between December 2020 and January 2021 to estimate the seroprevalence of SARS-CoV-2 infection among the general population and healthcare workers (HCWs) in India. Methods: The third serosurvey was conducted in the same 70 districts as the first and second serosurveys. For each district, at least 400 individuals aged >10 years from the general population and 100 HCWs from subdistrict-level health facilities were enrolled. Serum samples from the general population were tested for the presence of immunoglobulin G (IgG) antibodies against the nucleocapsid (N) and spike (S1-RBD) proteins of SARS-CoV-2, whereas serum samples from HCWs were tested for anti-S1-RBD. Weighted seroprevalence adjusted for assay characteristics was estimated. Results: Of the 28,598 serum samples from the general population, 4585 (16%) had IgG antibodies against the N protein, 6647 (23.2%) had IgG antibodies against the S1-RBD protein, and 7436 (26%) had IgG antibodies against either the N protein or the S1-RBD protein. Weighted and assay-characteristic adjusted seroprevalence against either of the antibodies was 24.1% [95% confidence interval (CI) 23.0- 25.3%]. Among 7385 HCWs, the seroprevalence of anti-S1-RBD IgG antibodies was 25.6% (95% CI 23.5- 27.8%). Conclusions: Nearly one in four individuals aged >10 years from the general population as well as HCWs in India had been exposed to SARS-CoV-2 by December 2020. (c) 2021 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-ncnd/4.0/).

引用

页码：145 / 155

页数：11

共 50 条

[21] SARS-CoV-2 seroprevalence among 7950 healthcare workers in the Region of Southern Denmark
von Huth, Sebastian
Lillevang, Soren Thue
Roge, Birgit Thorup
Madsen, Jonna Skov
Mogensen, Christian Backer
Coia, John Eugenio
Moller, Soren
Justesen, Ulrik Stenz
Johansen, Isik Somuncu
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2021, 112 : 96 - 102
[22] High Seroprevalence of SARS-CoV-2 among Healthcare Workers in a North Italy Hospital
Airoldi, Chiara
Patrucco, Filippo
Milano, Fulvia
Alessi, Daniela
Sarro, Andrea
Rossi, Maicol Andrea
Cena, Tiziana
Borre, Silvio
Faggiano, Fabrizio
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2021, 18 (07)
[23] SARS-COV-2 seroprevalence among all healthcare workers in a tertiary hospital in Spain
Cantero, Mireia
Millan-Perez, Rosario
Munez, Elena
Gomez-Lozano, Natalia
Anel-Pedroche, Jorge
Parra, Lina M.
Rodriguez, Maria L.
Asensio, Angel
INFECTIOUS DISEASES, 2022, 54 (01) : 8 - 15
[24] Clusters of SARS-CoV-2 Infection Among Elementary School Educators and Students in One School District- Georgia, December 2020-January 2021 (vol 70, pg 289, 2021)
Gold, J. A. W.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2021, 70 (10): : 364 - 364
[25] Severe acute respiratory coronavirus virus 2 (SARS-CoV-2) outbreak investigation in a hospital emergency department-California, December 2020-January 2021
Li, Ruoran
Beshearse, Elizabeth
Malden, Deborah
Truong, Holly
Kraushaar, Vit
Bonin, Brandon J.
Kim, Janice
Kennedy, Idamae
McNary, Jennifer
Han, George S.
Rudman, Sarah L.
Perz, Joseph F.
Perkins, Kiran M.
Glowicz, Janet
Epson, Erin
Benowitz, Isaac
Villarino, Elsa
INFECTION CONTROL & HOSPITAL EPIDEMIOLOGY, 2023, 44 (07) : 1187 - 1192
[26] Seroprevalence of antibodies to SARS-CoV-2 in healthcare workers & implications of infection control practice in India
Gupta, Ritu
Dwivedi, Tanima
Gajendra, Smeeta
Sahoo, Biswajeet
Gupta, Sanjeev Kumar
Vikas, H.
Singh, Angel Rajan
Mohan, Anant
Bhatnagar, Sushma
Singh, Sheetal
Wundavalli, Laxmitej
Guleria, Randeep
INDIAN JOURNAL OF MEDICAL RESEARCH, 2021, 153 (1-2) : 207 - 213
[27] SARS-CoV-2 Transmission in Alberta, British Columbia, and Ontario, Canada, January 2020-January 2022
Kehoe, Aubrey D.
Mallhi, Arshpreet Kaur
Barton, Charles R.
Martin, Hunter M.
Turner, Christopher M.
Hua, Xinyi
Kwok, Kin On
Chowell, Gerardo
Fung, Isaac Chun-Hai
EMERGING INFECTIOUS DISEASES, 2024, 30 (05) : 956 - 967
[28] Factors Associated with Participation in Elementary School-Based SARS-CoV-2 Testing - Salt Lake County, Utah, December 2020-January 2021
Lewis, Nathaniel M.
Hershow, Rebecca B.
Chu, Victoria T.
Wu, Karen
Milne, Alison T.
LaCross, Nathan
Hill, Mary
Risk, Ilene
Hersh, Adam L.
Kirking, Hannah L.
Tate, Jacqueline E.
Vallabhaneni, Snigdha
Dunn, Angela C.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2021, 70 (15): : 557 - 559
[29] Estimated Infection and Vaccine Induced SARS-CoV-2 Seroprevalence in Israel among Adults, January 2020-July 2021
Bassal, Ravit
Keinan-Boker, Lital
Cohen, Dani
Mendelson, Ella
Lustig, Yaniv
Indenbaum, Victoria
VACCINES, 2022, 10 (10)
[30] Seroprevalence of SARS-CoV-2 Among Workers in Northern Italy
Airoldi, Chiara
Calcagno, Andrea
Di Perri, Giovanni
Valinotto, Rosanna
Gallo, Lucia
Locana, Elisabetta
Trunfio, Mattia
Patrucco, Filippo
Vineis, Paolo
Faggiano, Fabrizio
ANNALS OF WORK EXPOSURES AND HEALTH, 2022, 66 (02) : 224 - 232

← 1 2 3 4 5 →