Evaluation of electrical characteristics of biological tissue with electrical impedance spectroscopy

被引:23
|
作者
Yao, Jiafeng [1 ]
Wang, Li [1 ]
Liu, Kai [1 ]
Wu, Hongtao [1 ]
Wang, Hao [2 ]
Huang, Jingshi [3 ]
Li, Jianping [4 ]
机构
[1] Nanjing Univ Aeronaut & Astronaut, Coll Mech & Elect Engn, Nanjing, Peoples R China
[2] Guangzhou 12 Hosp, Inst Otolaryngol, Guangzhou, Peoples R China
[3] Shanghai Univ Engn Sci, Sino Korean Sch Multimedia Design, Human LAB, Shanghai, Peoples R China
[4] Zhejiang Normal Univ, Coll Engn, Jinhua, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
Biomedical measurement; Electrical impedance spectroscopy; Equivalent circuit fitting; Least squares method; THYROID-NODULES; SURGERY;
D O I
10.1002/elps.201900420
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The electrical characteristics of biological tissue is evaluated by establishing an electrical equivalent circuit with electrical impedance spectroscopy. The least squares method is used to realize electrical equivalent circuit fitting by using the developed portable electrical impedance spectroscopy system. The EIS system is used to obtain the impedance spectrum data of the measured biological tissue. In the experiment, the impedance spectrum data of eggs under different heating time were measured, and the established equivalent circuit model of eggs was fitted by nonlinear least squares fitting algorithm. Moreover, the electrical characteristics of the biological tissue are also revealed by numerical simulation with HANAI model. The experimental and simulation results show that the extracted equivalent electrical parameters can clearly characterize the variation of the internal change of components of biological tissues.
引用
收藏
页码:1425 / 1432
页数:8
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