Cholesterol toxicity in pancreatic islets from LDL receptor-deficient mice

被引:6
|
作者
de Souza, J. C. [1 ]
de Oliveira, C. A. M. [1 ]
Carneiro, E. M. [1 ]
Boschero, A. C. [1 ]
de Oliveira, H. C. F. [1 ]
机构
[1] Univ Estadual Campinas, UNICAMP, Dept Anat Biol Celular Fisiol & Biofis, Inst Biol, BR-13083862 Campinas, SP, Brazil
关键词
Beta cell function; Cholesterol; Insulin secretion; LDL receptor; Pancreatic islets;
D O I
10.1007/s00125-010-1868-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2461 / 2462
页数:2
相关论文
共 50 条
  • [31] Systemic Inflammation Is Not Improved by Chronic Insulin Therapy in LDL Receptor-Deficient Mice
    Yoon, Jisung
    Subramanian, Savitha
    Ding, Yilei
    O'Brien, Kevin D.
    Chait, Alan
    DIABETES, 2010, 59 : A478 - A478
  • [32] Atherosclerosis in cholesterol-fed rabbits and in homozygous and heterozygous LDL receptor-deficient humans
    Thompson, Gilbert R.
    ATHEROSCLEROSIS, 2018, 276 : 148 - 154
  • [33] Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice
    Tsimikas, S
    Palinski, W
    Witztum, JL
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (01) : 95 - 100
  • [34] Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptor-deficient mice
    Rajavashisth, T
    Qiao, JH
    Tripathi, S
    Tripathi, J
    Mishra, N
    Hua, M
    Wang, XP
    Loussararian, A
    Clinton, S
    Libby, P
    Lusis, A
    JOURNAL OF CLINICAL INVESTIGATION, 1998, 101 (12): : 2702 - 2710
  • [35] Effect of streptozotocin-induced diabetes and a cholesterol-enriched diet on aortic atherosclerosis in LDL receptor-deficient mice
    Reaven, PD
    Casanada, F
    Sutphin, MS
    Palinski, W
    CIRCULATION, 1996, 94 (08) : 202 - 202
  • [36] Effect of γ-irradiation and bone marrow transplantation on atherosclerosis in LDL receptor-deficient mice
    Schiller, NK
    Kubo, N
    Boisvert, WA
    Curtiss, LK
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (10) : 1674 - 1680
  • [37] Hepatic expression of apolipoprotein E inhibits progression of atherosclerosis without reducing cholesterol levels in LDL receptor-deficient mice
    Tsukamoto, K
    Tangirala, RK
    Chun, S
    Usher, D
    Puré, E
    Rader, DJ
    MOLECULAR THERAPY, 2000, 1 (02) : 189 - 194
  • [38] Glucosamine supplementation accelerates early but not late atherosclerosis in LDL receptor-deficient mice
    Tannock, Lisa R.
    Kirk, Elizabeth A.
    King, Victoria L.
    LeBoeuf, Renee
    Wight, Thomas N.
    Chait, Alan
    JOURNAL OF NUTRITION, 2006, 136 (11): : 2856 - 2861
  • [39] Pregnane X Receptor Mediates Atherosclerosis Induced by Dicyclohexyl Phthalate in LDL Receptor-Deficient Mice
    Liu, Jingwei
    Hernandez, Rebecca
    Li, Xiuchun
    Meng, Zhaojie
    Chen, Hong
    Zhou, Changcheng
    CELLS, 2022, 11 (07)
  • [40] INCREASED AUTOANTIBODY TITERS AGAINST EPITOPES OF OXIDIZED LDL IN LDL RECEPTOR-DEFICIENT MICE WITH INCREASED ATHEROSCLEROSIS
    PALINSKI, W
    TANGIRALA, RK
    MILLER, E
    YOUNG, SG
    WITZTUM, JL
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1995, 15 (10) : 1569 - 1576