Synthesis of new polyether glycodendrons as oligosaccharide mimetics

被引：14
|
作者：
Elsner, Katharina [1 ]
Boysen, Mike M. K. [1 ]
Lindhorst, Thisbe K. [1 ]
机构：
[1] Univ Kiel, Otto Diels Inst Organ Chem, D-24098 Kiel, Germany
来源：
CARBOHYDRATE RESEARCH | 2007年 / 342卷 / 12-13期
关键词：
glycomimetics; glycodendrimers; mixed glycodendrons;
D O I：
10.1016/j.carres.2007.05.005
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Divalent and tetravalent glycomimetics based on polyether glycodendrons have been prepared. The branched scaffolds were decorated with galactose moieties on one hand and were elaborated into new glycodendrons of a 'mixed' type on the other, carrying both galactose and mannose moieties as biologically important sugar epitopes. All synthesized glycodendrons possess a focal point that can be employed for further derivatization and functionalization. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1715 / 1725
页数：11
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