Synthesis of new polyether glycodendrons as oligosaccharide mimetics

被引：14

作者：

Elsner, Katharina ^{[1
]}

Boysen, Mike M. K. ^{[1
]}

Lindhorst, Thisbe K. ^{[1
]}

机构：

[1] Univ Kiel, Otto Diels Inst Organ Chem, D-24098 Kiel, Germany

来源：

CARBOHYDRATE RESEARCH | 2007年 / 342卷 / 12-13期

关键词：

glycomimetics; glycodendrimers; mixed glycodendrons;

D O I：

10.1016/j.carres.2007.05.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Divalent and tetravalent glycomimetics based on polyether glycodendrons have been prepared. The branched scaffolds were decorated with galactose moieties on one hand and were elaborated into new glycodendrons of a 'mixed' type on the other, carrying both galactose and mannose moieties as biologically important sugar epitopes. All synthesized glycodendrons possess a focal point that can be employed for further derivatization and functionalization. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1715 / 1725

页数：11

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