Synthesis and Analgesic Studies of Some New 2-pyrazolines

被引：24

作者：

Sridhar, S. ^{[1
]}

Rajendraprasad, Y. ^{[2
]}

机构：

[1] Malla Reddy Coll Pharm, Dept Pharmaceut Chem, Secunderabad, India

[2] Andhra Univ, Univ Coll Pharmaceut Sci, Vishakapatanam, India

来源：

E-JOURNAL OF CHEMISTRY | 2012年 / 9卷 / 04期

关键词：

Pyrazolines; Analgesic activity; BIOLOGICAL EVALUATION;

D O I：

10.1155/2012/476989

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new series of 2-pyrazolines (4a-j) were synthesized by reacting chalcones (3a-j) with phenyl hydrazine in the presence of pyridine and ethanol. All these compounds were characterized by means of their IR, H-1-NMR spectral data and microanalyses. When these compounds were evaluated for analgesic activity, some of them were found to possess significant activity, when compared to standard drugs.

引用

页码：1810 / 1815

页数：6

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