Synthesis and Analgesic Studies of Some New 2-pyrazolines

被引：24
|
作者：
Sridhar, S. [1 ]
Rajendraprasad, Y. [2 ]
机构：
[1] Malla Reddy Coll Pharm, Dept Pharmaceut Chem, Secunderabad, India
[2] Andhra Univ, Univ Coll Pharmaceut Sci, Vishakapatanam, India
来源：
E-JOURNAL OF CHEMISTRY | 2012年 / 9卷 / 04期
关键词：
Pyrazolines; Analgesic activity; BIOLOGICAL EVALUATION;
D O I：
10.1155/2012/476989
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new series of 2-pyrazolines (4a-j) were synthesized by reacting chalcones (3a-j) with phenyl hydrazine in the presence of pyridine and ethanol. All these compounds were characterized by means of their IR, H-1-NMR spectral data and microanalyses. When these compounds were evaluated for analgesic activity, some of them were found to possess significant activity, when compared to standard drugs.
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页码：1810 / 1815
页数：6
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