Hydrogen-bonded supramolecular polymer micelles with pH/photothermal-responsive carmofur release and combined chemo-photothermal therapy

被引:10
|
作者
Wu, Yanggui [1 ]
Wang, Huiying [1 ]
Liu, Qianqian [2 ]
Lortie, Frederic [3 ]
Bernard, Julien [3 ]
Binder, Wolfgang H. [4 ]
Chen, Senbin [1 ]
Zhu, Jintao [1 ]
机构
[1] Huazhong Univ Sci & Technol HUST, Hubei Engn Res Ctr Biomat & Med Protect Mat, Sch Chem & Chem Engn, Wuhan 430074, Peoples R China
[2] Wuhan Inst Technol, Sch Mat Sci & Engn, Wuhan 430205, Peoples R China
[3] Univ Lyon, CNRS, INSA Lyon, IMP,UMR 5223, F-69621 Villeurbanne, France
[4] Martin Luther Univ Halle Wittenberg, Fac Nat Sci Chem Phys & Math 2, Chair Macromol Chem, Von Danckelmann Pl 4, D-06120 Halle, Saale, Germany
基金
中国国家自然科学基金;
关键词
DRUG-DELIVERY;
D O I
10.1039/d1py01634b
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Integrating biomedical applications (e.g., drug delivery) into supramolecular chemistry is a promising strategy. This work targets the construction of hydrogen-bonded (H-bonded) supramolecular polymeric micelles loaded with chemotherapy drugs (carmofur) and photothermal agents (IR780) for combined chemo-photothermal therapies (CT/PTT).
引用
收藏
页码:1010 / 1014
页数:5
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