Contribution of aquaporins in the transamniotic water flux

被引：2
|
作者：
Di Paola, Mauricio [1 ,2 ]
Sierra, Matias N. [1 ]
Fernandez, Nazarena [1 ]
Ibarra, Cristina [3 ]
Damiano, Alicia E. [1 ,2 ]
机构：
[1] Univ Buenos Aires, Fac Farm & Bioquim, Dept Ciencias Biol, Catedra Biol Celular & Mol, Junin 956 1er Piso, RA-1113 Buenos Aires, DF, Argentina
[2] Univ Buenos Aires, Fac Med, CONICET, Inst Fisiol & Biofis Bernardo Houssay IFIBIO,Lab, Buenos Aires, DF, Argentina
[3] Univ Buenos Aires, Fac Med, Dept Fisiol,Lab Fisiopatogenia, CONICET,Inst Fisiol & Biofis Bernardo Houssay IFI, Buenos Aires, DF, Argentina
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2022年 / 590卷
关键词：
AQPs; Amnion; Water transport; VOLUME; EXPRESSION; PLACENTA; SYSTEM;
D O I：
10.1016/j.bbrc.2021.12.097
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We explored the contribution of each aquaporin (AQP) expressed in human amnion in the transcellular water flux across the human amnion. Human amnion was placed between two lucite chambers and net water transport (Jw) was recorded by applying a hydrostatic (7 cm H2O) and an osmotic (40 mOsm PEG 8000) pressure gradients. The hydrostatic (Phydr) and osmotic (POsm) permeabilities were calculated before and after the blocking of AQPs. Phdr showed no significant difference after the blocking of AQPs, while POsm was dramatically reduced. Interestingly, we also found that the blocking of AQP1 produced the highest decrease of POsm (80 +/- 1%). Our results strongly suggested that AQP1 seems to contribute more to the maintenance of AF volume homeostasis. (C) 2021 Elsevier Inc. All rights reserved.
引用
收藏
页码：63 / 67
页数：5
相关论文
共 50 条
  • [1] Hydraulic conductivity and contribution of aquaporins to water uptake in roots of four sunflower genotypes
    Afifuddin Latif Adiredjo
    Olivier Navaud
    Philippe Grieu
    Thierry Lamaze
    Botanical Studies, 55
  • [2] Hydraulic conductivity and contribution of aquaporins to water uptake in roots of four sunflower genotypes
    Adiredjo, Afifuddin Latif
    Navaud, Olivier
    Grieu, Philippe
    Lamaze, Thierry
    BOTANICAL STUDIES, 2014, 55
  • [3] Contribution of aquaporins to cellular water transport observed by a microfluidic cell volume sensor
    Heo, Jinseok
    Meng, Fanjie
    Hua, Susan Z.
    ANALYTICAL CHEMISTRY, 2008, 80 (18) : 6974 - 6980
  • [4] Aquaporins and plant water balance
    Kaldenhoff, Ralf
    Ribas-Carbo, Miquel
    Flexas, Jaume
    Lovisolo, Claudio
    Heckwolf, Marlies
    Uehlein, Norbert
    PLANT CELL AND ENVIRONMENT, 2008, 31 (05): : 658 - 666
  • [5] Cerebral water channels - aquaporins
    Kozler, P
    Mohapl, M
    Pokorny, J
    Langmeier, M
    Trojan, S
    CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE, 2004, 67 (02) : 65 - 70
  • [6] The Discovery of Water Channels (Aquaporins)
    Brown, Dennis
    ANNALS OF NUTRITION AND METABOLISM, 2017, 70 : 37 - 42
  • [7] Aquaporins and water homeostasis in plants
    Kjellbom, P
    Larsson, C
    Johansson, I
    Karlsson, M
    Johanson, U
    TRENDS IN PLANT SCIENCE, 1999, 4 (08) : 308 - 314
  • [8] Thermodynamics of Water Entry in Aquaporins
    Farimani, Amir Barati
    Tajkhorshid, Emad
    Aluru, Narayana
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 559A - 559A
  • [9] Aquaporins in immune cells: contribution for inflammasome priming and activation
    da Silva, I. V.
    Cardoso, C.
    Martinez-Banaclocha, H.
    Casini, A.
    Pelegrin, P.
    Soveral, G.
    FEBS OPEN BIO, 2019, 9 : 71 - 72
  • [10] WHO DISCOVERED THE WATER CHANNELS (AQUAPORINS) ?
    Balaban, A. T.
    Haiduc, I.
    Matasa, C. G.
    Sha'afi, R. I.
    CELLULAR AND MOLECULAR BIOLOGY, 2006, 52 (07) : 6 - 7
12345