Novel Trimeric HIV-1 Clade C Envelope Vaccine Candidates Exhibit Increased Stability and Optimal Antigenic Properties In Vitro and In Vivo

被引：0
|
作者：
Hauser, Alexandra [1 ]
Peterhoff, David [1 ]
Hartinger, Theresa [1 ]
Friedrich, Nikolas [2 ]
Trkola, Alexandra [2 ]
Moog, Christiane [3 ]
Weissenhorn, Winfried [4 ]
Sanders, Rogier [5 ]
Sattentau, Quentin [6 ]
Wagner, Ralf [1 ]
机构：
[1] Univ Regensburg, Inst Med Microbiol & Hyg, Regensburg, Germany
[2] Univ Zurich, Zurich, Switzerland
[3] Univ Strasbourg, Strasbourg, France
[4] Inst Biol Struct, Grenoble, France
[5] Univ Amsterdam, Acad Med Ctr, Amsterdam, Netherlands
[6] Sir William Dunn Sch Pathol, Oxford, England
来源：
AIDS RESEARCH AND HUMAN RETROVIRUSES | 2018年 / 34卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
P19.17
引用
收藏
页码：320 / 320
页数：1
相关论文
共 36 条
  • [21] Structural features of a novel HIV-1 Indian clade C trimeric soluble Env SOSIP and the polyclonal neutralizing antibody responses developed in vaccinated rabbits
    Bhattacharya, J.
    Chandrawacar, A. Singh
    Dhiman, K.
    Sewall, L. M.
    Ozorowski, G.
    Cottrell, C. A.
    Hingankar, N.
    Kumar, R.
    Deshpande, S.
    Murugavel, K. G.
    Ashish, A.
    Ward, A. B.
    JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2021, 24
  • [22] Genetic and Neutralization Properties of HIV-1 India Clade C Envelope in Recent Infection: Correlation with CCR5 Usage and Clonal Divergence
    Ringe, R.
    Gharu, L.
    Satyakumar, A.
    Pandey, S.
    Thakar, M.
    Bhattacharya, J.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2008, 24 : 33 - 33
  • [23] Intravaginal immunization using the recombinant HIV-1 clade-C trimeric envelope glycoprotein CN54gp140 formulated within lyophilized solid dosage forms
    Donnelly, Louise
    Curran, Rhonda M.
    Tregoning, John S.
    McKay, Paul F.
    Cole, Tom
    Morrow, Ryan J.
    Kett, Vicky L.
    Andrews, Gavin P.
    Woolfson, A. David
    Malcolm, R. Karl
    Shattock, Robin J.
    VACCINE, 2011, 29 (27) : 4512 - 4520
  • [24] Pre-Clinical Development of a Recombinant, Replication-Competent Adenovirus Serotype 4 Vector Vaccine Expressing HIV-1 Envelope 1086 Clade C
    Alexander, Jeff
    Mendy, Jason
    Vang, Lo
    Avanzini, Jenny B.
    Garduno, Fermin
    Manayani, Darly J.
    Ishioka, Glenn
    Farness, Peggy
    Ping, Li-Hua
    Swanstrom, Ronald
    Parks, Robert
    Liao, Hua-Xin
    Haynes, Barton F.
    Montefiori, David C.
    LaBranche, Celia
    Smith, Jonathan
    Gurwith, Marc
    Mayall, Tim
    PLOS ONE, 2013, 8 (12):
  • [25] Vaginal Delivery of a Recombinant HIV-1 Clade-C Trimeric gp140 within Novel Rheologically Structured Vehicles Induces Specific Immune Responses
    Curran, R. M.
    Donnelly, L.
    Morrow, R.
    Andrews, G.
    Malcolm, K. R.
    Woolfson, D. A.
    Wegmann, F.
    Sattentau, Q.
    Cranage, M.
    Fraser, C.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2008, 24 : 151 - 151
  • [26] Vaginal delivery of the recombinant HIV-1 clade-C trimeric gp140 envelope protein CN54gp140 within novel rheologically structured vehicles elicits specific immune responses
    Curran, Rhonda M.
    Donnelly, Louise
    Morrow, Ryan J.
    Fraser, Carol
    Andrews, Gavin
    Cranage, Martin
    Malcolm, R. Karl
    Shattock, Robin J.
    Woolfson, A. David
    VACCINE, 2009, 27 (48) : 6791 - 6798
  • [27] Improved in vitro expression and in vivo immunogenicity of a candidate MVA-vectored HIV-1 vaccine compared to SAAVI MVA-C
    Douglass, N.
    Van Diepen, M.
    Chapman, R.
    Galant, S.
    Margolin, E.
    Ximba, P.
    Hermanus, T.
    Moore, P.
    Williamson, A. -L.
    JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2021, 24
  • [28] b12 Resistance in Acute Clade B and C HIV-1 Arises from Antigenic Variation within the CD4-Binding Loop and Steric Occlusion by Native Envelope Trimer
    Wu, X.
    Zhou, T.
    O'Dell, S.
    Wyatt, R.
    Kwong, P.
    Mascola, J.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2008, 24 : 52 - 52
  • [29] V2 hotspot optimized MVA vaccine expressing stabilized HIV-1 Clade C envelope Gp140 delays acquisition of heterologous Clade C Tier 2 challenges in Mamu-A*01 negative Rhesus Macaques
    Styles, Tiffany M.
    Gangadhara, Sailaja
    Reddy, Pradeep B. J.
    Sahoo, Anusmita
    Shiferaw, Ayalensh
    Welbourn, Sarah
    Kozlowski, Pamela A.
    Derdeyn, Cynthia A.
    Velu, Vijayakumar
    Amara, Rama Rao
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [30] Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence
    Rao, Vasudev R.
    Neogi, Ujjwal
    Talboom, Joshua S.
    Padilla, Ligia
    Rahman, Mustafizur
    Fritz-French, Cari
    Gonzalez-Ramirez, Sandra
    Verma, Anjali
    Wood, Charles
    Ruprecht, Ruth M.
    Ranga, Udaykumar
    Azim, Tasnim
    Joska, John
    Eugenin, Eliseo
    Shet, Anita
    Bimonte-Nelson, Heather
    Tyor, William R.
    Prasad, Vinayaka R.
    RETROVIROLOGY, 2013, 10
1234