A facile synthesis of 1-alkyl-5-arylalkoxy-6-methoxy-3,4-dihydroisoquinolines

被引:1
|
作者
Yim, Heong-Seup
Kim, Ho-Kyun
Kim, Jeum-Jong
Kweon, Deok-Heon
Lee, Sang-Gyeong [1 ]
Kim, Jung-Ho
Yoon, Yong-Jin
机构
[1] Gyeongsang Natl Univ, Grad Sch Mol Mat & Nanochem, Environm Biotechnol Natl Core Res Ctr, Res Inst Nat Sci,Dept Chem, Jinju 660701, South Korea
[2] Gyeongsang Natl Univ, Grad Sch Mol Mat & Nanochem, Res Inst Life Sci, Dept Chem, Jinju 660701, South Korea
[3] Hanwha Chem R&D Ctr, Taejon 305345, South Korea
关键词
D O I
10.1002/jhet.5570440426
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
1-Alkyl-5-arylalkoxy-6-methoxy-3,4-dihydroisoquinolines were synthesized by the alkylation of 1-alkyl-5-hydroxy-6-methoxy-3,4-dihydroisoquinolines with arylalkyl halide in the presence of potassium carbonate. 1-Alkyl-5-hydroxy-6-methoxy-3,4-dihydroisoquinolines as key precursor prepared from o-vaniline via 6 steps.
引用
收藏
页码:909 / 914
页数:6
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