Radio-guided surgery in neuroendocrine tumors

被引：22
|
作者：
Gulec, Seza A.
Baum, Richard
机构：
[1] Goshen Hlth Syst, Ctr Canc Care, Goshen, IN USA
[2] Zentralklin Bad Berka, PET Ctr, Clin Nucl Med, Bad Berka, Germany
来源：
JOURNAL OF SURGICAL ONCOLOGY | 2007年 / 96卷 / 04期
关键词：
neuroendocrine tumors; somatostatin receptor scintigraphy; somatostatin analog radiopharmacy;
D O I：
10.1002/jso.20868
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The majority of Neuroendocrine tumors (NET) express somatostatin (SS) receptors, and thus can be successfully targeted with radiolabeled SS analogs in vivo. Somatostatin receptor scintigraphy (SRS) with In-111-DTPA Octreotide is the main imaging technique for evaluation of NETs. Radio-guided surgery for NETs, therefore, primarily utilizes In-111-DTPA Octreotide tumor localization mechanism and kinetics. Somatostatin analog radiopharmacy continues to evolve to include the development of more selective and higher affinity analogs and PET tracers. These changes are expected to open new venues for radio-guided surgery technology.
引用
收藏
页码：309 / 315
页数：7
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