The Photophysical Properties of Multi-Functional Quantum Dots-Magnetic Nanoparticles-Indium Octacarboxyphthalocyanine Nanocomposite

被引:15
|
作者
Tshangana, Charmaine [1 ]
Nyokong, Tebello [1 ]
机构
[1] Rhodes Univ, Dept Chem, ZA-6140 Grahamstown, South Africa
基金
新加坡国家研究基金会;
关键词
Indium octacarboxyphthalocyanine; Quantum dots; Magnetite nanoparticles; Forster resonance energy transfer; Triplet quantum yields; SILICA NANOPARTICLES; MESOPOROUS SILICA; HYBRID NANOPARTICLES; PHOTODYNAMIC THERAPY; PHTHALOCYANINES; FLUORESCENT; DYE; EMISSION; BEHAVIOR; SYSTEM;
D O I
10.1007/s10895-014-1497-6
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This work presents the development of a multifunctional hybrid nanoparticle made of (L-)glutathione capped quantum dots (GSH-CdSe@ZnS), amino functionalized Fe3O4 magnetic nanoparticles and indium octacarboxy phthalocyanine (ClInPc(COOH)(8)). In this work we investigate the photophysical properties of the individual components and the hybrid nanoparticle, in addition we study the energy transfer (Forster Resonance Energy Transfer (FRET)) in the complex. FRET efficiencies of similar to 48 % were obtained for energy transfer between the QDs (when alone or linked to MNPs). Both triplet yields and lifetimes of ClInPc(COOH)(8) increase in the nanocomposite, with a decrease in fluorescence lifetime. The hybrid nanoparticle showed improved photophysical properties and as a result can be used in photodynamic therapy.
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页码:199 / 210
页数:12
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