Pectin-glycerol gel beads: Preparation, characterization and swelling behaviour

被引：36

作者：

Vityazev, Fedor V. ^{[1
]}

Khramova, Daria S. ^{[1
]}

Saveliev, Nikita Y. ^{[1
]}

Ipatova, Elena A. ^{[2
]}

Burkov, Andrey A. ^{[4
]}

Beloserov, Vladislav S. ^{[4
]}

Belyi, Vladimir A. ^{[2
]}

Kononov, Leonid O. ^{[3
]}

Martinson, Ekaterina A. ^{[4
]}

Litvinets, Sergey G. ^{[4
]}

Markov, Pavel A. ^{[1
]}

Popov, Sergey, V ^{[1
]}

机构：

[1] Russian Acad Sci, Urals Branch, Inst Physiol, FRC Komi SC UB RAS,Komi Sci Ctr, 50 Pervomaiskaya Str, Syktyvkar 167982, Russia

[2] Russian Acad Sci, Urals Branch, Inst Chem, FRC Komi SC UB RAS,Komi Sci Ctr, 48 Pervomaiskaya Str, Syktyvkar 167982, Russia

[3] ND Zelinskii Inst Organ Chem, 47 Leninsky Prospect, Moscow 119991, Russia

[4] Vyatka State Univ, Fed Govt Financed Educ Inst Higher Profess Educ, 36 Moskovskaya Str, Kirov 610000, Russia

来源：

CARBOHYDRATE POLYMERS | 2020年 / 238卷

基金：

俄罗斯科学基金会;

关键词：

Pectin; Glycerol; Gelling; FTIR spectra; Rheological properties; Swelling in gastrointestinal fluids; HIGH-METHOXY PECTIN; MECHANICAL-PROPERTIES; CONTROLLED DELIVERY; MUCOADHESIVE BEADS; DRUG; POLYSACCHARIDES; GELATION; ALGINATE; FILMS; ACID;

D O I：

10.1016/j.carbpol.2020.116166

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Low methyl-esterified pectin (AU701) was found to form gel beads with glycerol. We AU701-glycerol gel beads exhibited similar diameter and hardness compared to the AU701-Ca gel beads, prepared by ionotropic gelation with Ca2+ and used for comparison. The morphology of dry pectin gel beads determined by scanning electron microscopy revealed that the beads exhibited rough and grooved surface. The AU701-glycerol gel beads absorbed more grams of water than AU701-Ca gel beads (12.2 g vs 3.9 g per 1 g of the beads). Rheological properties and hardness of the AU701-glycerol gel beads improved with the increase of the pectin/glycerol ratio. Swelling behavior of the AU701-glycerol gel beads was determined after sequential incubation in simulated gastric (SGF) and intestinal (SIF) fluids. The AU701-glycerol gel beads swelled in SGF to a greater extent and revealed higher stability in SIF than the gel beads cross-linked by Ca2+.

引用

页数：15

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