To date there is no definite cure for ankylosing spondylitis. However, modern treatment improves the quality of life and the final outcome for most patients, Patient education and physiotherapy form the basis of treatment. In pharmaco therapy, nonsteroidal anti-inflammatory drugs have a central role. Second-line drugs such as sulfasalazine, immunomodulating agents and other antirheumatic disease-modifying drugs should be applied if the disease is active. Corticosteroids are used mainly intra-articularly, The problem of osteoporosis in ankylosing spondylitis is gaining more interest, and efforts to prevent or treat it will increase. It is critical to make an early diagnosis of ankylosing spondylitis and in active cases start intensive therapy before irreversible damage takes place.
机构:
Malaghan Inst Med Res, POB 7060, Wellington, New Zealand
Univ Otago, Wellington Sch Med, Dept Med, Wellington, New ZealandMalaghan Inst Med Res, POB 7060, Wellington, New Zealand
Grainger, Rebecca
Harrison, Andrew A.
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Univ Otago, Wellington Sch Med, Dept Med, Wellington, New ZealandMalaghan Inst Med Res, POB 7060, Wellington, New Zealand
机构:
Univ Hlth Network, Schroeder Arthrit Inst, Krembil Res Inst, Toronto, ON, CanadaUniv Hlth Network, Schroeder Arthrit Inst, Krembil Res Inst, Toronto, ON, Canada
Kusuda, Masaki
Haroon, Nigil
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Univ Hlth Network, Schroeder Arthrit Inst, Krembil Res Inst, Toronto, ON, Canada
Toronto Western Hosp, Univ Hlth Network, Div Rheumatol, Spondylitis Program, Toronto, ON, Canada
Univ Toronto, Temerty Fac Med, Div Rheumatol, Toronto, ON, Canada
Univ Toronto, Inst Med Sci, Temerty Fac Med, 399 Bathurst St, Toronto, ON M5T 2S8, CanadaUniv Hlth Network, Schroeder Arthrit Inst, Krembil Res Inst, Toronto, ON, Canada
Haroon, Nigil
Nakamura, Akihiro
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Univ Hlth Network, Schroeder Arthrit Inst, Krembil Res Inst, Toronto, ON, Canada
Toronto Western Hosp, Univ Hlth Network, Div Rheumatol, Spondylitis Program, Toronto, ON, Canada
Univ Toronto, Temerty Fac Med, Div Rheumatol, Toronto, ON, Canada
Univ Toronto, Inst Med Sci, Temerty Fac Med, 399 Bathurst St, Toronto, ON M5T 2S8, CanadaUniv Hlth Network, Schroeder Arthrit Inst, Krembil Res Inst, Toronto, ON, Canada