Preparation of vaterite/poly(lactic acid) composites with excellent apatite-forming ability

被引：3
|
作者：
Kasuga, T [1 ]
Maeda, H
Jell, G
Notingher, I
Hench, LL
机构：
[1] Nagoya Inst Technol, Grad Sch Engn, Dept Mat Sci & Engn, Showa Ku, Nagoya, Aichi 4668555, Japan
[2] Univ London Imperial Coll Sci Technol & Med, Dept Mat, London SW7 2BP, England
来源：
BIOCERAMICS 17 | 2005年 / 284-286卷
关键词：
apatite formation; biomineralization; calcium carbonate; composite; poly(lactic acid);
D O I：
10.4028/www.scientific.net/KEM.284-286.449
中图分类号：
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
A new type of ceramic-polymer biomaterial having excellent apatite-forming ability in simulated body fluid (SBF) was prepared by hot-pressing a mixture consisting of poly(-L-lactic acid) (PLA) and calcium carbonate (vaterite). The composite containing 30% vaterite showed no brittle fracture behavior and comparably high bending strength of similar to 50 MPa. Apatite layer of several micrometers in thickness formed on its surface after soaking in SBF at 37 degrees C only for 1 day. Osteoclast culture tests showed that the composite coated with apatite has excellent bioresorbability. After incubation of human osteoblasts, mineralized bone nodule formation was seen on the surface.
引用
收藏
页码：449 / 452
页数：4
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