An Overview of Vaccines against SARS-CoV-2 in the COVID-19 Pandemic Era

被引：28

作者：

Pascual-Iglesias, Alejandro ^{[1
,2
]}

Canton, Javier ^{[3
]}

Ortega-Prieto, Ana Maria ^{[4
]}

Jimenez-Guardeno, Jose M. ^{[4
]}

Regla-Nava, Jose Angel ^{[5
,6
]}

机构：

[1] La Paz Univ Hosp, IdiPAZ, Innate Immune Response Grp, Madrid 28046, Spain

[2] La Paz Univ Hosp, IdiPAZ, Tumor Immunol Lab, Madrid 28046, Spain

[3] Int Inst Def & Secur CISDE, Seville 41007, Spain

[4] Kings Coll London, Sch Immunol & Microbial Sci, Dept Infect Dis, London SE1 9RT, England

[5] Ctr Infect Dis & Vaccine Res, La Jolla Inst Immunol, La Jolla, CA 92037 USA

[6] Univ Guadalajara, Univ Ctr Hlth Sci CUCS, Dept Pathol & Microbiol, Guadalajara 44340, Mexico

来源：

PATHOGENS | 2021年 / 10卷 / 08期

关键词：

coronavirus; SARS-CoV-2; COVID-19; vaccine; clinical trial; pandemic; RESPIRATORY SYNCYTIAL VIRUS; ANIMAL-MODELS; CORONAVIRUS INFECTION; SARS; MERS; DISEASE; SAFETY; PATHOGENESIS; MUTATIONS; COUNTRIES;

D O I：

10.3390/pathogens10081030

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The emergence of SARS-CoV-2 in late 2019 led to the COVID-19 pandemic all over the world. When the virus was first isolated and its genome was sequenced in the early months of 2020, the efforts to develop a vaccine began. Based on prior well-known knowledge about coronavirus, the SARS-CoV-2 spike (S) protein was selected as the main target. Currently, more than one hundred vaccines are being investigated and several of them are already authorized by medical agencies. This review summarizes and compares the current knowledge about main approaches for vaccine development, focusing on those authorized and specifically their immunogenicity, efficacy preventing severe disease, adverse side effects, protection, and ability to cope with emergent SARS-CoV-2 variants.

引用

页数：21

共 50 条

[21] COVID-19: An Overview of SARS-CoV-2 Variants-The Current Vaccines and Drug Development
Bostanghadiri, Narjess
Ziaeefar, Pardis
Mofrad, Morvarid Golrokh
Yousefzadeh, Parsa
Hashemi, Ali
Darban-Sarokhalil, Davood
BIOMED RESEARCH INTERNATIONAL, 2023, 2023
[22] Ramadan Fasting in SARS-CoV-2 (COVID-19) Pandemic
Akbari, Mojtaba
Jalali, Arefe Khaksar
Ansari, Hossein
Soltanian, Noureddin
HEALTH SCOPE, 2020, 9 (03):
[23] The Complexity of SARS-CoV-2 Infection and the COVID-19 Pandemic
da Silva Torres, Maria Karoliny
Bichara, Carlos David Araujo
de Almeida, Maria de Nazare do Socorro
Vallinoto, Mariana Cayres
Queiroz, Maria Alice Freitas
Vallinoto, Izaura Maria Vieira Cayres
dos Santos, Eduardo Jose Melo
de Carvalho, Carlos Alberto Marques
Vallinoto, Antonio Carlos R.
FRONTIERS IN MICROBIOLOGY, 2022, 13
[24] Laboratory evaluation of SARS-CoV-2 in the COVID-19 pandemic
Parikh, Bijal A.
Farnsworth, Christopher W.
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY, 2021, 35 (01):
[25] SARS-CoV-2 variants and ending the COVID-19 pandemic
Fontanet, Arnaud
Autran, Brigitte
Lina, Bruno
Kieny, Marie Paule
Karim, Salim S. Abdool
Sridhar, Devi
LANCET, 2021, 397 (10278): : 952 - 954
[26] Potential Utility of Radiopharmaceuticals in the Battle Against SARS-Cov-2 and COVID-19 Pandemic
Sager, Omer
Dincoglan, Ferrat
Demiral, Selcuk
Beyzadeoglu, Murat
CURRENT RADIOPHARMACEUTICALS, 2022, 15 (02) : 93 - 95
[27] SARS-CoV-2/COVID-19 Vaccines: The Promises and the Challenges Ahead
Baldo, Vincenzo
Reno, Chiara
Cocchio, Silvia
Fantini, Maria Pia
VACCINES, 2021, 9 (01)
[28] SARS-COV-2 MUTATIONS AND VARIATIONS AND HOW COVID-19 VACCINES WORK AGAINST THE VARIANTS
Nowakowska, Elzbieta
Michalska, Joanna
Michalak, Sylwia Sulimiera
Paczkowska, Anna
ACTA POLONIAE PHARMACEUTICA, 2021, 78 (03): : 291 - 303
[29] Immunological memory to SARS-CoV-2 infection and COVID-19 vaccines
Sette, Alessandro
Crotty, Shane
IMMUNOLOGICAL REVIEWS, 2022, 310 (01) : 27 - 46
[30] Vaccine against COVID-19 or against SARS-CoV-2 infection?
Rieske, Piotr
ALERGOLOGIA POLSKA-POLISH JOURNAL OF ALLERGOLOGY, 2020, 7 (03) : 131 - 145

← 1 2 3 4 5 →