PIK3CA hotspot mutations are present at a relatively high frequency in CTCs of operable and metastatic breast cancer patients

被引：0
|
作者：
Markou, Athina N. [1 ]
Farkona, Sofia [1 ]
Schiza, Christina [1 ]
Eftathiou, Antonia [1 ]
Malamos, Nikolaos [2 ]
Georgoulias, Vassilis [3 ]
Lianidou, Evi [1 ]
机构：
[1] Univ Athens, Dept Chem, Anal Circulating Tumor Cells Lab, Analyt Chem Lab, GR-10680 Athens, Greece
[2] Elena Venizelou Hosp, Med Oncol Unit, Athens, Greece
[3] Univ Crete, Sch Med, Tumor Cell Biol Lab, Iraklion, Greece
来源：
CANCER RESEARCH | 2014年 / 74卷 / 19期
关键词：
D O I：
10.1158/1538-7445.AM2014-3067
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3067
引用
收藏
页数：1
相关论文
共 50 条
  • [41] PIK3CA Mutations May Be Discordant between Primary and Corresponding Metastatic Disease in Breast Cancer
    Jensen, Jeanette Dupont
    Laenkholm, Anne-Vibeke
    Knoop, Ann
    Ewertz, Marianne
    Bandaru, Raj
    Liu, Weihua
    Hackl, Wolfgang
    Barrett, J. Carl
    Gardner, Humphrey
    CLINICAL CANCER RESEARCH, 2011, 17 (04) : 667 - 677
  • [42] Prognostic and Predictive Value of PIK3CA Mutations in Metastatic Colorectal Cancer
    Tan, Elaine S.
    Fan, Wenyi
    Knepper, Todd C.
    Schell, Michael J.
    Sahin, Ibrahim H.
    Fleming, Jason B.
    Xie, Hao
    TARGETED ONCOLOGY, 2022, 17 (04) : 483 - 492
  • [43] Prognostic and Predictive Value of PIK3CA Mutations in Metastatic Colorectal Cancer
    Elaine S. Tan
    Wenyi Fan
    Todd C. Knepper
    Michael J. Schell
    Ibrahim H. Sahin
    Jason B. Fleming
    Hao Xie
    Targeted Oncology, 2022, 17 : 483 - 492
  • [44] Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
    Chen, Li
    Yang, Liu
    Yao, Ling
    Kuang, Xia-Ying
    Zuo, Wen-Jia
    Li, Shan
    Qiao, Feng
    Liu, Yi-Rong
    Cao, Zhi-Gang
    Zhou, Shu-Ling
    Zhou, Xiao-Yan
    Yang, Wen-Tao
    Shi, Jin-Xiu
    Huang, Wei
    Hu, Xin
    Shao, Zhi-Ming
    NATURE COMMUNICATIONS, 2018, 9
  • [45] Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients
    Li Chen
    Liu Yang
    Ling Yao
    Xia-Ying Kuang
    Wen-Jia Zuo
    Shan Li
    Feng Qiao
    Yi-Rong Liu
    Zhi-Gang Cao
    Shu-Ling Zhou
    Xiao-Yan Zhou
    Wen-Tao Yang
    Jin-Xiu Shi
    Wei Huang
    Xin Hu
    Zhi-Ming Shao
    Nature Communications, 9
  • [46] An Analysis of PIK3CA Hotspot Mutations and Response to Neoadjuvant Therapy in Patients with Breast Cancer from Four Prospective Clinical Trials
    Jank, Paul
    Karn, Thomas
    van Mackelenbergh, Marion
    Lindner, Judith
    Treue, Denise
    Huober, Jens
    Engels, Knut
    Solbach, Christine
    Diebold, Kurt
    Marme, Frederik
    Mueller, Volkmar
    Schneeweiss, Andreas
    Sinn, Hans-Peter
    Fehm, Tanja
    Schem, Christian
    Stickeler, Elmar
    Fasching, Peter
    Budczies, Jan
    Felder, Baerbel
    Nekljudova, Valentina
    Holtschmidt, Johannes
    Untch, Michael
    Denkert, Carsten
    Loibl, Sibylle
    CLINICAL CANCER RESEARCH, 2024, 30 (17) : 3868 - 3880
  • [47] PIK3CA and PTEN mutations in adenoid cystic carcinoma of the breast metastatic to kidney
    Vranic, Semir
    Bilalovic, Nurija
    Lee, Lisa M. J.
    Kruslin, Bozo
    Litleberg, Stan L.
    Gatatica, Zoran
    HUMAN PATHOLOGY, 2007, 38 (09) : 1425 - 1431
  • [48] Increased MAPK1/3 Phosphorylation in Luminal Breast Cancer Related with PIK3CA Hotspot Mutations and Prognosis
    Ramirez-Ardila, Diana
    Timmermans, A. Mieke
    Helmijr, Jean A.
    Martens, John W. M.
    Berns, Els M. J. J.
    Jansen, Maurice P. H. M.
    TRANSLATIONAL ONCOLOGY, 2017, 10 (05): : 854 - 867
  • [49] PIK3CA exon 20 mutations are associated with poor prognosis in breast cancer patients
    Mangone, Flavia R.
    Bobrovnitchaia, Irina G.
    Salaorni, Sibeli
    Manuli, Erika
    Nagai, Maria A.
    CLINICS, 2012, 67 (11) : 1285 - 1290
  • [50] PIK3CA mutations in serum DNA are predictive of recurrence in primary breast cancer patients
    Chiya Oshiro
    Naofumi Kagara
    Yasuto Naoi
    Masafumi Shimoda
    Atsushi Shimomura
    Naomi Maruyama
    Kenzo Shimazu
    Seung Jin Kim
    Shinzaburo Noguchi
    Breast Cancer Research and Treatment, 2015, 150 : 299 - 307
12345