Emerging Oral Therapies for Multiple Sclerosis

被引:1
|
作者
Miller, Colleen E. [1 ]
Umhauer, Margaret A. [1 ]
机构
[1] SUNY Buffalo, William C Baird Multiple Sclerosis Res Ctr, Jacobs Neurol Inst, Buffalo, NY 14260 USA
关键词
NOVO RENAL-TRANSPLANTATION; PLACEBO-CONTROLLED TRIAL; FUMARIC-ACID ESTERS; DOUBLE-BLIND; FINGOLIMOD FTY720; PHASE-II; MULTICENTER; CLADRIBINE; LAQUINIMOD; TERIFLUNOMIDE;
D O I
10.1097/JNN.0b013e31820297a9
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Despite notable advances in the understanding of multiple sclerosis (MS) and the availability of several treatment options, there is a need for therapies that are more effective, safe, convenient, and well tolerated. Several new oral MS therapies are being investigated. Because data on these new therapies continue to emerge, nurses will play a pivotal role in educating patients regarding the benefits and risks of potential treatments and in monitoring patients for response, safety, tolerability, and adherence. This article reviews the oral MS therapies recently approved as well as those currently in development or submitted for Food and Drug Administration approval.
引用
收藏
页码:3 / 14
页数:12
相关论文
共 50 条
  • [21] Emerging oral drugs for multiple sclerosis
    Gasperini, Claudio
    Cefaro, Luca Ausili
    Borriello, Giovanna
    Tosto, Giuseppe
    Prosperini, Luca
    Pozzilli, Carlo
    [J]. EXPERT OPINION ON EMERGING DRUGS, 2008, 13 (03) : 465 - 477
  • [22] Overview of oral and IV therapies for multiple sclerosis
    Kappos, Ludwig
    [J]. MULTIPLE SCLEROSIS, 2008, 14 : S20 - S20
  • [23] First oral therapies for multiple sclerosis anticipated
    Bethan Hughes
    [J]. Nature Reviews Drug Discovery, 2009, 8 : 831 - 833
  • [24] First oral therapies for multiple sclerosis anticipated
    Hughes, Bethan
    [J]. NATURE REVIEWS DRUG DISCOVERY, 2009, 8 (11) : 831 - U9
  • [25] Oral therapies for multiple sclerosis: are we there yet?
    Hartung, Hans-Peter
    Aktas, Orhan
    [J]. LANCET NEUROLOGY, 2010, 9 (05): : 454 - 457
  • [26] Emerging therapies to target CNS pathophysiology in multiple sclerosis
    Jiwon Oh
    Amit Bar-Or
    [J]. Nature Reviews Neurology, 2022, 18 : 466 - 475
  • [27] Current and emerging therapies in multiple sclerosis: a systematic review
    Castro-Borrero, Wanda
    Graves, Donna
    Frohman, Teresa C.
    Flores, Angela Bates
    Hardeman, Paula
    Logan, Diana
    Orchard, Megan
    Greenberg, Benjamin
    Frohman, Elliot M.
    [J]. THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS, 2012, 5 (04) : 205 - 220
  • [28] Treatment Options for Multiple Sclerosis: Current and Emerging Therapies
    Gawronski, Kristen M.
    Rainka, Michelle M.
    Patel, Malti J.
    Gengo, Francis M.
    [J]. PHARMACOTHERAPY, 2010, 30 (09): : 916 - 927
  • [29] Emerging Therapies in Relapsing-Remitting Multiple Sclerosis
    Marriott, James J.
    O'Connor, Paul W.
    [J]. REVIEWS ON RECENT CLINICAL TRIALS, 2010, 5 (03) : 179 - 188
  • [30] Emerging Disease-Modifying Therapies in Multiple Sclerosis
    Jai Perumal
    Omar Khan
    [J]. Current Treatment Options in Neurology, 2012, 14 : 256 - 263