Auditory event-related potentials in Parkinson's disease: Prominent correlation with attention

被引：22

作者：

Matsui, Hideaki ^{[1
]}

Nishinaka, Kazuto ^{[1
]}

Oda, Masaya ^{[1
]}

Kubori, Tamotsu ^{[1
]}

Udaka, Fukashi ^{[1
]}

机构：

[1] Sumitomo Hosp, Dept Neurol, Kita Ku, Osaka 5300005, Japan

来源：

PARKINSONISM & RELATED DISORDERS | 2007年 / 13卷 / 07期

关键词：

Parkinson's disease; dementia; auditory event-related potentials; P300; attention;

D O I：

10.1016/j.parkreldis.2006.12.012

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: Auditory P300 has been reported to be abnormal in demented patients with Parkinson's disease. However, it is still controversial which factors in Parkinson's disease influence P300 parameters. Methods: Forty patients with Parkinson's disease were included. Patients were divided into two groups: patients with dementia (PDD) and without dementia (PDND). An `odd-ball' paradigm was used for auditory event-related potentials. Results: P300 latency was markedly delayed in PDD patients. Age and DRSI (attention) were the most important factors influencing P300 latency. Conclusions: Although there have been reports of P300 in the past, its abnormalities reflect the deficit of attention in Parkinson's disease. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：394 / 398

页数：5

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