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Results of the Dry Eye Research Grant Award 2016
被引:0
|作者:
Musayeva, A.
[1
]
Gericke, A.
[1
]
Jaeger, F.
[2
]
Paulsen, F.
[2
]
Braun, M.
[3
]
Fabry, B.
[3
]
Braun, R.
[4
]
Pauly, D.
[4
]
Holtmann, C.
[5
]
Geerling, G.
[5
]
机构:
[1] Klinikum Johannes Gutenberg Univ Mainz, Augenklin & Poliklin, Mainz, Germany
[2] FAU Erlangen Nurnberg, Inst Funkt & Klin Anat, Erlangen, Germany
[3] FAU Erlangen Nurnberg, Inst Phys Kondensierten Materie, Erlangen, Germany
[4] Univ Klinikum Regensburg, Klin & Poliklin Augenheilkunde, Regensburg, Germany
[5] Univ Klinikum Dusseldorf, Klin Augenheilkunde, Moorenstr 5, D-40225 Dusseldorf, Germany
来源:
关键词:
Muscarinic receptor;
Urea;
Tear film stability;
Graft versus host disease;
Eyelid tension;
MUSCARINIC ACETYLCHOLINE-RECEPTORS;
OCULAR SURFACE;
TEAR FLUID;
CHRONIC GVHD;
DISEASE;
BIOMARKERS;
SECRETION;
UREA;
CYTOKINES;
PROTEINS;
D O I:
10.1007/s00347-020-01163-w
中图分类号:
R77 [眼科学];
学科分类号:
100212 ;
摘要:
TheSicca-Forderpreis(Dry Eye Award) supports the development of scientific research on the pathogenesis, diagnostics, and treatment of dry eye and ocular surface diseases. It is awarded after a limited call for proposals in German-speaking countries, written application and selection of the award winner after evaluation by a jury of ophthalmologists working in basic and clinical science. In this article examples of the results of funded projects of theSicca-Forderpreis 2016are cursorily described, which were presented at the Ophthalmological Academy of Germany 2019 (Augenarztliche Akademie Deutschland 2019) and therefore provide an insight into current scientific developments. The role of muscarinic receptors and those of urea in the pathogenesis of dry eye as well as the (missing) correlation of tear film stability, viscosity and surface tension are highlighted. A project on the early detection of ocular involvement in graft versus host disease and the idea of treating meibomian gland dysfunction with eyelid surgery techniques are also groundbreaking. The outlined projects represent the potential for further substantial developments in the understanding, diagnostics and treatment of dry eye; however, their long-term clinical relevance still needs to be established.
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页码:337 / 344
页数:8
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