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- [21] Structural optimization of thiol-based inhibitors of glutamate carboxypeptidase II by modification of the P1′ side chainJOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (10) : 2876 - 2885Majer, Pavel论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USAHin, Bunda论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USAStoermer, Doris论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USAAdams, Jessica论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USAXu, Weizheng论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USADuvall, Bridget R.论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USADelahanty, Greg论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USALiu, Qun论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USAStathis, Marigo J.论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USAWozniak, Krystyna M.论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USASlusher, Barbara S.论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USATsukamoto, Takashi论文数: 0 引用数: 0 h-index: 0机构: MGI Pharma Inc, Baltimore, MD 21224 USA MGI Pharma Inc, Baltimore, MD 21224 USA
- [22] Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moietiesBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (21) : 5584 - 5589Pinto, Donald J. P.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USA Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USAGalemmo, Robert A., Jr.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USAQuan, Mimi L.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USAOrwat, Michael J.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USAClark, Charles论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USALi, Renhua论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USAWells, Brian论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USAWoerner, Francis论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USAAlexander, Richard S.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USARossi, Karen A.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USASmallwood, Angela论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USAWong, Pancras C.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USALuettgen, Joseph M.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USARendina, Alan R.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USAKnabb, Robert M.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USAHe, Kan论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USAWexler, Ruth R.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USALam, Patrick Y. S.论文数: 0 引用数: 0 h-index: 0机构: Discovery Chem Bristol Myers Squibb Pharmaceut Re, Princeton, NJ 08543 USA
- [23] Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: The discovery of GW0385BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (07) : 1788 - 1794Miller, JF论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USAAndrews, CW论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USABrieger, M论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USAFurfine, ES论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USAHale, MR论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USAHanlon, MH论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USAHazen, RJ论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USAKaldor, I论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USAMcLean, EW论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USAReynolds, D论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USASarnmond, DM论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USASpaltenstein, A论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USATung, R论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USATurner, EM论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USAXu, RX论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USASherrill, RG论文数: 0 引用数: 0 h-index: 0机构: GlaxoSmithKline Inc, Res Triangle Pk, NC 27709 USA
- [24] Discovery of a novel, selective, and orally bioavailable class of thrombin inhibitors incorporating aminopyridyl moieties at the P1 positionPEPTIDES: FRONTIERS OF PEPTIDES SCIENCE, 1999, : 672 - 673Feng, DM论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USAFreidinger, RM论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USALevis, SD论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USAGardell, SJ论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USABock, MG论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USAChen, ZG论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USANaylor-Olsen, A论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USAWoltmann, R论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USABaskin, EP论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USALynch, JJ论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USALucas, R论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USAShafer, JA论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USADancheck, KB论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USAChen, IW论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USAVacca, JP论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA Merck Res Labs, Dept Med Chem, W Point, PA 19486 USA
- [25] Discovery of α-Ketoamide inhibitors of SARS-CoV-2 main protease derived from quaternized P1 groupsBIOORGANIC CHEMISTRY, 2024, 143Huang, Qiao论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R ChinaQuan, Baoxue论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Canc Ctr, Dept Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R ChinaChen, Yan论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Canc Ctr, Dept Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R ChinaZhao, Xiu论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Canc Ctr, Dept Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R ChinaZhou, Yanmei论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Canc Ctr, Dept Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R ChinaHuang, Chong论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Canc Ctr, Dept Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R ChinaQiao, Jingxin论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Canc Ctr, Dept Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R ChinaWang, Yifei论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Canc Ctr, Dept Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R ChinaLi, Yueyue论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Canc Ctr, Dept Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R ChinaYang, Shengyong论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Canc Ctr, Dept Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China Frontier Med Ctr, Tianfu Jincheng Lab, Chengdu 610212, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R ChinaLei, Jian论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Hosp, Canc Ctr, Dept Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Hosp, Natl Clin Res Ctr Geriatr, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R ChinaLi, Linli论文数: 0 引用数: 0 h-index: 0机构: Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R China Sichuan Univ, West China Sch Pharm, Key Lab Drug Targeting & Drug Delivery Syst, Minist Educ, Chengdu 610041, Sichuan, Peoples R China
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