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- [43] Piperine, a functional food alkaloid, exhibits inhibitory potential against TNBS-induced colitis via the inhibition of IκB-α/NF-κB and induces tight junction protein (claudin-1, occludin, and ZO-1) signaling pathway in experimental mice HUMAN & EXPERIMENTAL TOXICOLOGY, 2020, 39 (04) : 477 - 491