Suprasellar malignant mixed germ cell tumour presenting as craniopharyngioma

被引:0
|
作者
Nada, R
Mohan, H
Dhir, SP
Mukherjee, KK
Kak, VK
机构
[1] Govt Med Coll, Dept Pathol, Chandigarh 160032, India
[2] Govt Med Coll, Dept Ophthalmol, Chandigarh 160032, India
[3] Govt Med Coll, Dept Neurosurg, Chandigarh 160032, India
关键词
germ cell tumour; suprasellar; craniopharyngioma; MRI;
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
A 15 year old boy presented with diminution in vision of both eyes, diabetes insipidus and hypopituitarism, MRI was suggestive of a large suprasellar and retrosellar craniopharyngioma with stretching of the optic chiasma. Histopathological findings on the first surgical specimen were interpreted as a craniopharyngioma, He was reoperated on account of clinical deterioration and increase in tumour size. Histological examination this time revealed derivatives of all three germ cell lineages along with areas of embryonal carcinoma, and yolk sac tumour besides squamous cysts, establishing the diagnosis of malignant mixed germ cell tumour. Serum and CSF were strongly positive for alpha foetoproteins.
引用
收藏
页码:381 / 384
页数:4
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