GPBAR1 (TGR5) IS A MODULATOR OF LIVER IMMUNITY AND REVERSES LIVER INFLAMMATION IN A MOUSE MODELS OF ACUTE HEPATITIS

被引:0
|
作者
Biagioli, Michele
Carino, Adriana
Fiorucci, Chiara
Marchiano, Silvia
Zampella, Angela
Distrutti, Eleonora
Fiorucci, Stefano
机构
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
241
引用
收藏
页码:S1078 / S1078
页数:1
相关论文
共 50 条
  • [1] Role of TGR5 (GPBAR1) in Liver Disease
    Keitel, Verena
    Haeussinger, Dieter
    SEMINARS IN LIVER DISEASE, 2018, 38 (04) : 333 - 339
  • [2] GPBAR1 (TGR5) AGONISM REVERSES ENDOTHELIAL DYSFUNCTION AND LIVER INJURY IN A DIETETIC MODEL OF STEATOHEPATITIS
    Carino, Adriana
    Marchiano, Silvia
    Biagioli, Michele
    Zampella, Angela
    Distrutti, Eleonora
    Fiorucci, Stefano
    Fiorucci, Chiara
    GASTROENTEROLOGY, 2018, 154 (06) : S1 - S1
  • [3] Optimization of sulfonamide based GPBAR1 (TGR5) agonists
    Huang, Chia-Yu
    Shi, Dongchuan
    Kultgen, Steven
    Healy, Jason
    Li, Yanfang
    Cole, Andrew
    Nawoschik, Stanley
    Tovar, Kiersten
    Fanelli, Barbara
    Ma, Xiaoquing
    Ebert-Gallo, Christina
    Hayward, Michael
    Nickels, Joseph
    Stein, Philip
    Webb, Maria
    McGuinness, Brian
    Beasley, James
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
  • [4] GPBAR1 (TGR5) agonists with low systemic exposure
    Huang, Chia-Yu
    Sieber-McMaster, Ellen
    Xu, Xiaoqing
    Nawoschik, Stanley
    Tovar, Kiersten
    Fanelli, Barbara
    Ma, Xiaoquing
    Ebert-Gallo, Christina
    Hayward, Michael
    Nickels, Joseph
    Stein, Philip
    Webb, Maria
    McGuinness, Brian
    Beasley, James
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
  • [5] BAR 501, a Novel GPBAR1 Ligand, Reverses Intestinal and Liver Inflammatory Models Demonstrating That GPBAR1 Is an Essential Modulator of Innate Immunity in Entero-Hepatic Tissues
    Cipriani, Sabrina
    Renga, Barbara
    Simonetti, Michele
    Carino, Adriana
    Zampella, Angela
    Fiorucci, Stefano
    GASTROENTEROLOGY, 2016, 150 (04) : S815 - S815
  • [6] GPBAR1 IS A MODULATOR OF LIVER IMMUNITY AND ITS AGONISM REVERSES ACETAMINOPHEN-INDUCED HEPATOTOXICITY BY MODULATING RECRUITMENT OF LIVER MACROPHAGES
    Biagioli, Michele
    Carino, Adriana
    Marchiano, Silvia
    Fiorucci, Chiara
    Bordoni, Martina
    Roselli, Rosalinda
    Di Giorgio, Cristina
    Distrutti, Eleonora
    Zampella, Angela
    Fiorucci, Stefano
    GASTROENTEROLOGY, 2019, 156 (06) : S1052 - S1052
  • [7] Perspective: TGR5 (Gpbar-1) in liver physiology and disease
    Keitel, Verena
    Haeussinger, Dieter
    CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY, 2012, 36 (05) : 412 - 419
  • [8] The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver
    Klindt, Caroline
    Reich, Maria
    Hellwig, Birte
    Stindt, Jan
    Rahnenfuehrer, Joerg
    Hengstler, Jan G.
    Koehrer, Karl
    Schoonjans, Kristina
    Haeussinger, Dieter
    Keitel, Verena
    CELLS, 2019, 8 (11)
  • [9] A Small Molecule TGR5 (GPBAR1) Agonist Shows Metabolic and Anti-Inflammatory Effects in Cells Expressing Human TGR5
    Chin, Janice E.
    Bernardo, Barbara L.
    Brenner, Martin B.
    Buxton, Joanne
    Cheng, John B.
    Futatsugi, Kentaro
    Gautreau, Denise
    Hadcock, John R.
    Hinchey, Terri
    Janssen, Ann
    Kelly-Sullivan, Dawn
    Piotrowski, David W.
    Roush, Nicole
    Orr, Suvi
    Warmus, Joseph
    Wolford, Angela
    DIABETES, 2013, 62 : A525 - A525
  • [10] Role of the bile acid receptor TGR5 (Gpbar-1) in liver damage and regeneration
    Verena Keitel
    Maria Reich
    Annika Sommerfeld
    Stefanie Kluge
    Ralf Kubitz
    Dieter Häussinger
    European Journal of Medical Research, 19