An ELISA assay for measuring the survival of motor neurons (SMN) protein and the search for a drug treatment for spinal muscular atrophy

被引：0
|
作者：
Man, NT
Lam, LT
Lynch, T
Sewry, C
MacKenzie, A
Morris, GE
机构：
[1] Robert Jones & Agnes Hunt Orthopaed Hosp, CIND, Oswestry SY10 7AG, Shrops, England
[2] Childrens Hosp Eastern Ontario, Ottawa, ON K1H 8L1, Canada
来源：
NEUROMUSCULAR DISORDERS | 2005年 / 15卷 / 9-10期
关键词：
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：726 / 726
页数：1
相关论文
共 50 条
  • [21] Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?
    Burghes, Arthur H. M.
    Beattie, Christine E.
    NATURE REVIEWS NEUROSCIENCE, 2009, 10 (08) : 597 - 609
  • [22] Molecular Determination of Survival Motor Neuron Protein SMN in Spinal Muscular Atrophy by Affinity Mass Spectrometry of Specific Proteotypic Peptides
    Przybylski, Michael
    Wiegand, Pascal
    Maeser, Stefan
    Kleinekofort, Wolfgang
    Hahn, Andreas
    JOURNAL OF PEPTIDE SCIENCE, 2022, 28
  • [23] Towards a treatment for spinal muscular atrophy: looking for drugs that increase SMN protein levels
    Man, MNT
    Lam, LT
    Stockwell, BR
    McKenzie, AE
    Morris, GE
    Sewry, CA
    NEUROMUSCULAR DISORDERS, 2004, 14 (8-9) : 595 - 596
  • [24] Bone loss in survival motor neuron (Smn-/- SMN2) genetic mouse model of spinal muscular atrophy
    Shanmugarajan, Srinivasan
    Tsuruga, Eichi
    Swoboda, Kathryn J.
    Maria, Bernard L.
    Ries, William L.
    Reddy, Sakamuri V.
    JOURNAL OF PATHOLOGY, 2009, 219 (01): : 52 - 60
  • [25] Characterization of survival motor neuron (SMN(T)) gene deletions in asymptomatic carriers of spinal muscular atrophy
    Wang, CH
    Xu, J
    Carter, TA
    Ross, BM
    Dominski, MK
    Bellcross, CA
    Penchaszadeh, GK
    Munsat, TL
    Gilliam, TC
    HUMAN MOLECULAR GENETICS, 1996, 5 (03) : 359 - 365
  • [26] SMN-inducing compounds for the treatment of spinal muscular atrophy
    Lorson, Monique A.
    Lorson, Christian L.
    FUTURE MEDICINAL CHEMISTRY, 2012, 4 (16) : 2067 - 2084
  • [27] Detection of human survival motor neuron (SMN) protein in mice containing the SMN2 transgene: Applicability to preclinical therapy development for spinal muscular atrophy
    Mattis, Virginia B.
    Butchbach, Matthew E. R.
    Lorson, Christian L.
    JOURNAL OF NEUROSCIENCE METHODS, 2008, 175 (01) : 36 - 43
  • [28] Effects of Astroglia on Motor Neurons in Spinal Muscular Atrophy
    Verheijen, Bert M.
    JOURNAL OF NEUROSCIENCE, 2017, 37 (36): : 8578 - 8580
  • [29] Recombinant SMN protein synergizes with spinal muscular atrophy therapy to counteract pathological motor neuron phenotypes
    Brambilla, Liliana
    Valori, Chiara F.
    Guidotti, Giulia
    Martorana, Francesca
    Sulmona, Claudia
    De Martini, Lisa Benedetta
    Canciani, Anselmo
    Fumagalli, Marco
    Talpo, Francesca
    Biella, Gerardo
    Di Pasquale, Elisa
    Iacobucci, Claudio
    Forneris, Federico
    Zhou, Haiyan
    Rossi, Daniela
    TRANSLATIONAL NEURODEGENERATION, 2024, 13 (01):
  • [30] Molecular analysis of survival motor neuron (SMN) and neuronal apoptosis inhibitory protein (NAIP) genes of spinal muscular atrophy patients and their parents
    Chang, JG
    Jong, YJ
    Lin, SP
    Soong, BW
    Tsai, CH
    Yang, TY
    Chang, CP
    Wang, WS
    HUMAN GENETICS, 1997, 100 (5-6) : 577 - 581
12345