A Robust and Scalable Continuous Flow Process for Glycerol Carbonate

被引：17

作者：

Van Mileghem, Seger ^{[1
,2
]}

De Borggraeve, Wim M. ^{[2
]}

Baxendale, Ian R. ^{[1
]}

机构：

[1] Univ Durham, Dept Chem, South Rd, Durham DH1 3LE, England

[2] Katholieke Univ Leuven, Div Mol Design & Synth, Dept Chem, Celestijnenlaan 200F, B-3001 Heverlee, Belgium

来源：

CHEMICAL ENGINEERING & TECHNOLOGY | 2018年 / 41卷 / 10期

关键词：

Flow chemistry; Glycerol carbonate; Valorization of glycerol; POLYMER-SUPPORTED REAGENTS; MULTISTEP ORGANIC-SYNTHESIS; DIMETHYL CARBONATE; CATALYZED SYNTHESIS; TRANSESTERIFICATION; SCAVENGERS; LIPASE; EPICHLOROHYDRIN; VALORIZATION; SIMULATION;

D O I：

10.1002/ceat.201800012

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

With glycerol being a bulk waste product, the interest in converting it to other value-added products is steadily increasing. A scalable continuous flow process was developed for the synthesis of glycerol carbonate (2-GLC) from glycerol and dimethyl carbonate on a hydroxide functional resin. High conversion and selectivity were obtained while the residence times were typically shorter than 10 min. Continuous production of 2-GLC was achieved in high throughput and with improved processing metrics, creating the foundations for a production level process.

引用

页码：2014 / 2023

页数：10

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