Specific Allergy Immunotherapy for Allergic Rhinitis: Subcutaneous and Sublingual

被引：27

作者：

Cox, Linda ^{[1
]}

Wallace, Dana ^{[1
]}

机构：

[1] Nova SE Univ, Sch Osteopath Med, Davie, FL USA

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2011年 / 31卷 / 03期

关键词：

Allergen immunotherapy; Sublingual immunotherapy; Allergic rhinitis; Subcutaneous immunotherapy; HOUSE-DUST-MITE; GRASS-POLLEN IMMUNOTHERAPY; PARTIALLY PURIFIED EXTRACT; SUMMER HAY-FEVER; DOUBLE-BLIND; CLINICAL-EFFICACY; FOLLOW-UP; SWALLOW IMMUNOTHERAPY; RESPIRATORY ALLERGY; ECONOMIC-EVALUATION;

D O I：

10.1016/j.iac.2011.05.001

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Numerous controlled clinical trials have demonstrated the efficacy of specific allergen immunotherapy (SIT) in reducing the clinical symptoms and costs associated with allergic rhinitis. Compared with pharmacotherapy, SIT may provide persistent clinical benefits after treatment discontinuation. Subcutaneous and sublingual immunotherapy are the two most widely prescribed SIT routes worldwide. This review compares the efficacy, safety, preventive effect, immunologic mechanisms, and adherence rates associated with these two forms of SIT.

引用

页码：561 / +

页数：40

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