Allylmalonate as an Activator Subunit for the Initiation of Relay Ring-Closing Metathesis Reactions

被引：8
|
作者：
Hoye, Thomas R. [1 ]
Jeon, Junha [1 ]
Tennakoon, Manomi A. [1 ]
机构：
[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 09期
基金：
美国国家卫生研究院;
关键词：
cyclization; metathesis; reaction mechanisms; ruthenium; CATALYSTS; EFFICIENT; INSIGHTS; STRATEGY; ANALOG;
D O I：
10.1002/anie.201005044
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Passing the baton: The relay ring-closing metathesis (RRCM) reaction of complex polyenes 1 has been studied. Several relay subunits (T) were examined and many did not sufficiently activate the RRCM. An allylmalonate-containing relay subunit solved this problem, and efficiently lead to the diene 2. TIPS=triisopropylsilyl. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：2141 / 2143
页数：3
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