What's Sex Got to Do With It? Understanding Potential Confounding and Exposure Misclassification in Mechanistic Sexually Transmitted Infection Research

被引：2

作者：

Deese, Jennifer ^{[1
]}

Wang, Meng ^{[2
]}

Lapple, Dana ^{[3
]}

Nelson, Julie A. E. ^{[4
]}

Kuerten, Bethany ^{[5
]}

Steiner, Markus J. ^{[6
]}

Chen, Pai Lien ^{[7
]}

Hobbs, Marcia M. ^{[3
]}

机构：

[1] RTI Int, Global Publ Hlth Impact Ctr, Res Triangle Pk, NC 27709 USA

[2] Target PharmaSolut, Durham, NC USA

[3] Univ N Carolina, Dept Med, Chapel Hill, NC 27515 USA

[4] Univ N Carolina, Dept Microbiol & Immunol, Chapel Hill, NC 27515 USA

[5] Upstream USA, Raleigh, NC USA

[6] FHI 360, Prod Dev & Intro, Durham, NC USA

[7] FHI 360, Biostat, Durham, NC USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 2021年 / 224卷 / 01期

关键词：

cytokine; HIV; prostate-specific antigen; sexually transmitted infection; PROSTATE-SPECIFIC ANTIGEN; SEMINAL PLASMA; CONTRACEPTION; INFLAMMATION; FLUID;

D O I：

10.1093/infdis/jiaa705

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We conducted a prospective study of 13 heterosexual couples to understand the impact of recent condomless vaginal sex on vaginal immune marker measurement and potential exposure misclassification due to the presence of semen. All immune markers were detectable in semen and concentrations of vaginal immune markers varied by sex recency.

引用

页码：137 / 140

页数：4