Radiation therapy toxicity to the skin

被引：23

作者：

FitzGerald, T. J. ^{[1
]}

Jodoin, Maryann Bishop ^{[1
]}

Tillman, Gayle ^{[1
]}

Aronowitz, Jesse ^{[1
]}

Pieters, Richard ^{[1
]}

Baiducci, Susan ^{[1
]}

Meyer, Joshua ^{[1
]}

Cicchetti, M. Giulia ^{[1
]}

Kadish, Sidney ^{[1
]}

McCauley, Shelagh ^{[1
]}

Sawicka, Joanna ^{[1
]}

Urie, Marcia ^{[1
]}

Lo, Y. C. ^{[1
]}

Mayo, Charles ^{[1
]}

Ulin, Kenneth ^{[1
]}

Ding, Linda ^{[1
]}

Britton, Maureen ^{[1
]}

Huang, Jiayi ^{[1
]}

Arous, Edward ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Mem Hlth Care, Ctr Canc,Dept Radiat Oncol, Worcester, MA 01655 USA

来源：

DERMATOLOGIC CLINICS | 2008年 / 26卷 / 01期

关键词：

D O I：

10.1016/j.det.2007.08.005

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Radiation therapy has been integral to cancer patient care. The skin is an intentional and unintentional target of therapy, and is sensitive to the volume of normal tissue in the radiation therapy treatment field, daily treatment dose (fractionation), and total treatment dose. We must understand the relationship of these factors to patient outcome as we move toward hypofractionation treatment strategies (radiosurgery). Chemotherapy agents and prescription medications may influence therapy-associated sequelae. Understanding this may prevent significant injury and discomfort. This article reviews established platforms of radiation therapy and sequelae associated with skin therapy. Interactions with other agents and possible predisposition to sequelae are reviewed. Skin cancer resulting from treatment and disease processes associated with possible limited outcome are also reviewed.

引用

页码：161 / +

页数：13

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