PULSAR open-label extension: interim results from a phase 2 study of the efficacy and safety of sotatercept when added to standard of care for the treatment of pulmonary arterial hypertension (PAH)

被引：0

作者：

Badesch, David ^{[1
]}

Gibbs, Simon ^{[2
]}

Gomberg-Maitland, Mardi ^{[3
]}

Hoeper, Marius ^{[4
,5
]}

Mclaughlin, Vallerie ^{[6
]}

Preston, Ioana ^{[7
]}

Souza, Rogerio ^{[8
]}

Waxman, Aaron ^{[9
]}

Manimaran, Solaiappan ^{[10
]}

Barnes, Jennifer ^{[10
]}

Pena, Janethe De Oliveira ^{[10
]}

Humbert, Marc ^{[11
]}

Hoeper, Marius M. ^{[12
]}

机构：

[1] Univ Colorado, Aurora, CO USA

[2] Imperial Coll London, Natl Heart & Lung Inst, London, England

[3] George Washington Univ, Washington, DC USA

[4] Hannover Med Sch, Dept Resp Med, Hannover, Germany

[5] German Ctr Lung Res, Hannover, Germany

[6] Univ Michigan, Ann Arbor, MI 48109 USA

[7] Tufts Med Ctr, Boston, MA 02111 USA

[8] InCor Univ Sao Paulo, Sao Paulo, Brazil

[9] Brigham & Womens Hosp, Boston, MA USA

[10] Acceleron Pharma, Cambridge, England

[11] Univ Paris Saclay, Assistance Publ Hop Paris, Le Kremlin Bicetre, France

[12] Univ Paris Saclay, Hannover, Germany

来源：

EUROPEAN RESPIRATORY JOURNAL | 2021年 / 58卷

关键词：

Pulmonary hypertension;

D O I：

10.1183/13993003.congress-2021.OA140

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

OA140

引用

页数：2

共 50 条

[1] PULSAR Study Open-Label Extension: Interim Results from a Phase 2 Study of the Efficacy and Safety of Sotatercept When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH)
Badesch, D. B.
Gibbs, S.
Gomberg-Maitland, M.
Hoeper, M. M.
McLaughlin, V. V.
Preston, I
Souza, R.
Waxman, A. B.
Manimaran, S.
Barnes, J.
Pena, J. de Oliveira
Humbert, M.
[J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2021, 203 (09)
[2] PULSAR Open-Label Extension: Long-Term Efficacy and Safety of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (PAH)
Humbert, M.
Mclaughlin, V. V.
Gibbs, S. R.
Gomberg-Maitland, M.
Hoeper, M.
Preston, I. R.
Souza, R.
Waxman, A. B.
Ghofrani, H. A.
Subias, P. Escribano
Feldman, J. P.
Bohns Meyer, G.
Montani, D.
Olsson, K. M.
Manimaran, S.
Pena, J. de Oliveira
Badesch, D. B.
[J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2022, 205
[3] Sotatercept for the treatment of pulmonary arterial hypertension: PULSAR open-label extension
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Hoeper, Marius M.
Preston, Ioana R.
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Olsson, Karen M.
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[J]. EUROPEAN RESPIRATORY JOURNAL, 2023, 61 (01)
[4] PULSAR: phase 2, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of sotatercept (ACE-on) when added to standard of care (SOC) for treatment of pulmonary arterial hypertension (PAH)
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Gibbs, Simon
Gomberg-Maitland, Mardi
Humbert, Marc
Mclaughlin, Vallerie
Preston, Ioana
Souza, Rogerio
Waxman, Aaron
Pena, Janethe De Oliveira
Barnes, Jennifer
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Zeldin, Robert K.
[J]. EUROPEAN RESPIRATORY JOURNAL, 2019, 54
[5] Interim Results from the Ongoing Open-Label Extension of the Phase 2 Trial Evaluating Ralinepag for the Treatment of Pulmonary Arterial Hypertension
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[J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199
[6] The SPECTRA Study: A Phase 2a Single-Arm, Open-Label, Multicenter Exploratory Study to Assess the Effects of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (PAH)
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[8] EFFICACY AND SAFETY OF 108 WEEKS' BIMEKIZUMAB TREATMENT IN PATIENTS WITH PSORIATIC ARTHRITIS: INTERIM RESULTS FROM A PHASE 2 OPEN-LABEL EXTENSION STUDY
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[J]. ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 : 1149 - 1150
[9] Cardiopulmonary Best Abstract Award: Improves Right Ventricular - Pulmonary Arterial Coupling and Right Ventricular Function in the Pulsar Study: A Phase 2, Double-blind, Placebo-controlled, Randomized Study to Compare the Efficacy and Safety of Sotatercept versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH)
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