Lipase-catalyzed kinetic resolution of 4-(N-Boc-amino)-1-alken-3-ols

被引：7
|
作者：
Oshitari, T [1 ]
Mandai, T [1 ]
机构：
[1] Kurashiki Univ Sci & Arts, Dept Chem & Biosci, Kurashiki, Okayama 7128505, Japan
来源：
SYNLETT | 2003年 / 15期
关键词：
4-(N-Boc-arnino); 1-alken-3-ols; kinetic resolution; lipase; the taxol side chain;
D O I：
10.1055/s-2003-42115
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A wide range of 4-(N-Boc-amino)-1-alken-3-ols were efficiently resolved by lipase-catalyzed kinetic resolution. This procedure has been successfully applied to the highly enantioselective synthesis of the taxol side chain.
引用
收藏
页码：2374 / 2376
页数：3
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