American Thoracic Society guidelines;
antibiotic resistance;
antibiotics;
empiric therapy;
hospital-acquired pneumonia;
nosocomial pneumonia;
patient quality of care;
D O I:
10.1378/chest.119.2_suppl.412S
中图分类号:
R4 [临床医学];
学科分类号:
1002 ;
100602 ;
摘要:
Hospital-acquired pneumonia (HAP) is associated with high morbidity and mortality. Early, appropriate, and adequate empiric therapy can increase the chance of survival. In 1995, the American Thoracic Society provided guidelines for the initial treatment of immunocompetent HAP patients, which is one of the principal HAP management approaches available to physicians today. However, these guidelines have several important limitations, including a lack of recommendations for duration of therapy and no recognition of newer drugs such as cefepime, trovafloxacin, and meropenem. Furthermore, they fail to distinguish among similar compounds tie, beta -lactam/beta -lactamase inhibitor combinations) or to recommend specific antibiotics. The clinician using these guidelines needs to address local patterns of antimicrobial resistance, especially in ICUs, Effective computerized antibiotic management programs that incorporate information on local patterns of antimicrobial resistance can assist physicians in empiric therapy decision making, improve patient quality of care, and reduce medical costs.
机构:
Aix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Leone, Marc
Bouadma, Lila
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机构:
Hop Bichat Claude Bernard, Serv Reanimat Med, 46 Rue Henri Huchard, F-75018 Paris, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Bouadma, Lila
Bouhemad, Belaid
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机构:
CHU Dijon, Serv Anesthesie Animat, BP 77908, F-21709 Dijon, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Bouhemad, Belaid
Brissaud, Olivier
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机构:
Univ Bordeaux II, CHU Pellegrin, Hop Pellegrin Enfants, Unite Reanimat Pediat, Pl Amelie Raba Leon, F-33076 Bordeaux, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Brissaud, Olivier
Dauger, Stephane
论文数: 0引用数: 0
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机构:
Paris Diderot Paris 7 Univ, Robert Debre Univ Hosp, AP HP, Inserm,U1141, 48 Blvd Serurier, F-75019 Paris, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Dauger, Stephane
Gibot, Sebastien
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机构:
Hop Cent, Serv Reanimat Med, 29 Ave Lattre de Tassigny, F-54035 Nancy, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Gibot, Sebastien
Hraiech, Sami
论文数: 0引用数: 0
h-index: 0
机构:
Assistance Publ Hop Marseille, Hop Nord, Serv Reanimat Etresses Resp & Infect Severes, F-13015 Marseille, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Hraiech, Sami
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Jung, Boris
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Kipnis, Eric
Launey, Yoann
论文数: 0引用数: 0
h-index: 0
机构:
Rennes Univ Hosp, Dept Anesthesia & Crit Care Med, F-35000 Rennes, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Launey, Yoann
Luyt, Charles-Edouard
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机构:
Univ Paris 6 Pierre & Marie Curie, Grp Hosp Pitie Salpetriere, AP HP, Inst Cardiol,Serv Reanimat Med, F-75000 Paris, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Luyt, Charles-Edouard
Margetis, Dimitri
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机构:
Hop St Antoine, AP HP, Serv Reanimat Med, 184 Rue Faubourg St Antoine, F-75012 Paris, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Margetis, Dimitri
Michel, Fabrice
论文数: 0引用数: 0
h-index: 0
机构:
Assistance Publ Hop Marseille, Timone Childrens Hosp, Anesthesia & Intens Care Unit, F-13005 Marseille, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Michel, Fabrice
Mokart, Djamel
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机构:
Paoli Calmettes Inst, Intens Care Unit, 232 Blvd St Marguerite, F-13009 Marseille, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Mokart, Djamel
Montravers, Philippe
论文数: 0引用数: 0
h-index: 0
机构:
Univ Paris VII Sorbonne Cite, CHU Bichat Claude Bernard, AP HP, Dept Anesthesie Reanimat, 46 Rue Henri Huchard, F-75018 Paris, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Montravers, Philippe
Monsel, Antoine
论文数: 0引用数: 0
h-index: 0
机构:
Univ Paris 06, Dept Anesthesiol & Crit Care, F-75000 Paris, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Monsel, Antoine
Nseir, Saad
论文数: 0引用数: 0
h-index: 0
机构:
CHU Lille, Crit Care Ctr, Dept Intens Care Med, F-59000 Lille, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Nseir, Saad
Pugin, Jerome
论文数: 0引用数: 0
h-index: 0
机构:
Hop Univ Geneve, CH-27230 Geneva, GE, SwitzerlandAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Pugin, Jerome
Roquilly, Antoine
论文数: 0引用数: 0
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机构:
Ctr Hosp Univ, Anaesthesia Intens Care Unit, F-44000 Nantes, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Roquilly, Antoine
Velly, Lionel
论文数: 0引用数: 0
h-index: 0
机构:
Hop La Timone, Dept Anesthesie Reanimat, F-13000 Marseille, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Velly, Lionel
Zahar, Jean-Ralph
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机构:
CHU Avicenne, Grp Hosp Paris Seine St Denis,AP HP, Dept Microbiol Clin, Unite Controle Prevent,Risque Infect, 125 Rue Stalingrad, F-93000 Bobigny, France
Univ Paris 13, Sorbonne Paris Cite, UMR 1137, Infect Control Unit,IAME, F-75000 Paris, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Zahar, Jean-Ralph
Bruyere, Remi
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机构:
Ctr Hosp Bourg En Bresse, Serv Reanimat, 900 Route Paris, F-01000 Bourg En Bresse, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
Bruyere, Remi
Chanques, Gerald
论文数: 0引用数: 0
h-index: 0
机构:
Hop La Timone, Dept Anesthesie Reanimat, F-13000 Marseille, France
CHU Montpellier, Hop St Eloi, Dept Anesthesie Reanimat, 80 Ave Augustin Fliche, F-34295 Montpellier 5, France
Univ Montpellier, CNRS, INSERM, U1046,UMR 9214,PhyMedExp, F-34295 Montpellier 5, FranceAix Marseille Univ, Hop Nord, AP HM, Serv Anesthesie Reanimat, F-13015 Marseille, France
机构:
Washington Univ, Sch Med, Div Pulm & Crit Care Med, 4523 Clayton Ave,Campus Box 8052, St Louis, MO 63110 USAWashington Univ, Sch Med, Div Pulm & Crit Care Med, 4523 Clayton Ave,Campus Box 8052, St Louis, MO 63110 USA
Lyons, Patrick G.
Kollef, Marin H.
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机构:
Washington Univ, Sch Med, Div Pulm & Crit Care Med, 4523 Clayton Ave,Campus Box 8052, St Louis, MO 63110 USAWashington Univ, Sch Med, Div Pulm & Crit Care Med, 4523 Clayton Ave,Campus Box 8052, St Louis, MO 63110 USA
机构:
McMaster Univ & Henderson Site, Div Infect Dis, Hamilton, ON, Canada
McMaster Univ & Henderson Site, Dept Med, Hamilton, ON, CanadaMcMaster Univ & Henderson Site, Div Infect Dis, Hamilton, ON, Canada
Rotstein, Coleman
Evans, Gerald
论文数: 0引用数: 0
h-index: 0
机构:
Queens Univ, Div Infect Dis, Kingston, ON K7L 3N6, Canada
Kingston Gen Hosp, Kingston, ON, CanadaMcMaster Univ & Henderson Site, Div Infect Dis, Hamilton, ON, Canada
Evans, Gerald
Born, Abraham
论文数: 0引用数: 0
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机构:
Univ Toronto, Toronto, ON, Canada
N York Gen Hosp, Toronto, ON, CanadaMcMaster Univ & Henderson Site, Div Infect Dis, Hamilton, ON, Canada
Born, Abraham
Grossman, Ronald
论文数: 0引用数: 0
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机构:
Univ Toronto, Ontario & Credit Valley Hosp, Mississauga, ON L5L 1C6, CanadaMcMaster Univ & Henderson Site, Div Infect Dis, Hamilton, ON, Canada
Grossman, Ronald
Light, R. Bruce
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机构:
Univ Manitoba, Winnipeg, MB, Canada
St Boniface Gen Hosp, Winnipeg, MB, CanadaMcMaster Univ & Henderson Site, Div Infect Dis, Hamilton, ON, Canada
Light, R. Bruce
Magder, Sheldon
论文数: 0引用数: 0
h-index: 0
机构:
McGill Univ, Ctr Hlth, Div Crit Care, Montreal, PQ, Canada
Royal Victoria Hosp, Dept Med, Montreal, PQ H3A 1A1, CanadaMcMaster Univ & Henderson Site, Div Infect Dis, Hamilton, ON, Canada
Magder, Sheldon
McTaggart, Barrie
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h-index: 0
机构:
McMaster Univ, Med Ctr, Hamilton, ON, CanadaMcMaster Univ & Henderson Site, Div Infect Dis, Hamilton, ON, Canada
机构:
John Innes Ctr, Norwich, Norfolk, England
Univ East Anglia, Norwich, Norfolk, EnglandJohn Innes Ctr, Norwich, Norfolk, England
Russell, Alicia H.
Horner, Carolyne
论文数: 0引用数: 0
h-index: 0
机构:
British Soc Antimicrobial Chemotherapy, Birmingham, W Midlands, EnglandJohn Innes Ctr, Norwich, Norfolk, England
Horner, Carolyne
Livermore, David M.
论文数: 0引用数: 0
h-index: 0
机构:
Univ East Anglia, Norwich, Norfolk, England
Publ Hlth England, London, EnglandJohn Innes Ctr, Norwich, Norfolk, England
Livermore, David M.
MacGowan, Alasdair P.
论文数: 0引用数: 0
h-index: 0
机构:
British Soc Antimicrobial Chemotherapy, Birmingham, W Midlands, England
Southmead Hosp North Bristol NHS Trust, Bristol, Avon, EnglandJohn Innes Ctr, Norwich, Norfolk, England
机构:
Weill Cornell Med, Div Pulm & Crit Care Med, New York, NY USAUniv Barcelona, Hosp Clin Barcelona, Dept Pulmonol, IDIBAPS,CIBERES Barcelona, Barcelona, Spain
机构:
Washington Univ, Sch Med, Pulm & Crit Care Div, St Louis, MO USAUniv Barcelona, Hosp Clin Barcelona, Dept Pulmonol, IDIBAPS,CIBERES Barcelona, Barcelona, Spain
Kollef, Marin
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Bassi, Gianluigi Li
Luna, Carlos M.
论文数: 0引用数: 0
h-index: 0
机构:
Washington Univ, Sch Med, Pulm & Crit Care Div, St Louis, MO USA
Univ Buenos Aires, Hosp Clin Jose de San Martin, Pulm Dis Div, Dept Med, Buenos Aires, DF, ArgentinaUniv Barcelona, Hosp Clin Barcelona, Dept Pulmonol, IDIBAPS,CIBERES Barcelona, Barcelona, Spain