Odour Transduction in Olfactory Receptor Neurons

被引：12
|
作者：
Rospars, Jean-Pierre [1 ]
Gu, Yuqiao [1 ]
Gremiaux, Alexandre [1 ]
Lucas, Philippe [1 ]
机构：
[1] INRA, UMR Physiol Insecte Signalisat & Commun 1272, F-78000 Versailles, France
来源：
CHINESE JOURNAL OF PHYSIOLOGY | 2010年 / 53卷 / 06期
基金：
英国生物技术与生命科学研究理事会;
关键词：
olfactory receptors; ionic channels; OBPs; pheromones; computer models; PHOSPHOLIPASE-C-BETA; PHEROMONE RECEPTOR; MOLECULAR-BASIS; CHEMOSENSORY SIGNALS; CATION CHANNEL; ION CHANNELS; RESPONSES; PROTEIN; MODEL; GENE;
D O I：
10.4077/CJP.2010.AMM038
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
The molecular mechanisms that control the binding of odorant to olfactory receptors and transduce this signal into membrane depolarization are reviewed. They are compared in vertebrates and insects for interspecific (allelochemicals) and intraspecific (pheromones) olfactory signals. Attempts to develop quantitative models of these multistage signalling networks are presented. Computational analysis of olfactory transduction is still in its infancy and appears as a promising area for future developments.
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页码：364 / 372
页数：9
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