Synthesis of dimethylbipyridines by the reductive coupling of 2-halomethylpyridines with nickel catalyst

被引：5
|
作者：
Rajalakshmanan, E [1 ]
Alexander, V [1 ]
机构：
[1] Loyola Coll, Dept Chem, Madras 600034, Tamil Nadu, India
来源：
SYNTHETIC COMMUNICATIONS | 2005年 / 35卷 / 06期
关键词：
4,4 '-dimethyl-2,2 '-bipyridine; 6,6 '-dimethyl-2,2-bipyridine; modified Ullmann-type coupling; nickel(0) catalyst; reductive coupling of 2-halomethylpyridines;
D O I：
10.1081/SCC-200051056
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The one-pot synthesis of 4,4'-dimethyl-2,2'-bipyridine and 6,6'-dimethyl-2,2'-bipyridine by the reductive coupling of 2-bromo-4-methylpyridine and 2-bromo-6-methylpyridine, respectively, with nickel catalyst, generated in situ by the reduction of Ni(PPh3)(2)Cl-2 with zinc in the presence of Et4NI, is described.
引用
收藏
页码：891 / 895
页数：5
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